Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect

Mosleh-Shirazi, Sareh; Kasaee, Seyed Reza; Dehghani, Fatemehsadat; Kamyab, Hesam; Kirpichnikova, Irina; Chelliapan, Shreeshivadasan; Firuzyar, Tahereh; Akhtari, Mohammadreza; Amani, Ali Mohammad

doi:10.1016/j.ceramint.2022.11.329

Cited by 58 publications

(9 citation statements)

References 60 publications

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“… 113 These NPs preferentially absorb and convert light spectrum into heat when exposed to near-infrared light, which leads to localized hyperthermia and the destruction of cancer cells while minimizing harm to healthy tissues. 166 …”

Section: Biomedical Applications Of Green Synthesized Npsmentioning

confidence: 99%

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Ahmad,

Ali

et al. 2024

IJN

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Green synthesis of silver (Ag) and gold (Au) nanoparticles (NPs) has acquired huge popularity owing to their potential applications in various fields. A large number of research articles exist in the literature describing the green synthesis of Ag and Au NPs for biomedical applications. However, these findings are scattered, making it time-consuming for researchers to locate promising advancements in Ag and Au NPs synthesis and their unexplored biomedical applications. Unlike other review articles, this systematic study not only highlights recent advancements in the green synthesis of Ag and Au NPs but also explores their potential unexplored biomedical applications. The article discusses the various synthesis approaches for the green synthesis of Ag and Au NPs highlighting the emerging developments and novel strategies. Then, the article reviews the important biomedical applications of green synthesized Ag and Au NPs by critically evaluating the expected advantages. To expose future research direction in the field, the article describes the unexplored biomedical applications of the NPs. Finally, the articles discuss the challenges and limitations in the green synthesis of Ag and Au NPs and their biomedical applications. This article will serve as a valuable reference for researchers, working on green synthesis of Ag and Au NPs for biomedical applications.

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Section: Biomedical Applications Of Green Synthesized Npsmentioning

confidence: 99%

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Ahmad,

Ali

et al. 2024

IJN

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“…Nanotechnology can be harnessed for the targeted delivery of therapeutic drugs or dyes for imaging of specific cancer cells [ 31 ]. Further, several metal nanoparticles are reported to be specifically inhibitory to cancer cells, thus they have potential in the direct targeted killing of cancerous cells, with minimum side effects when compared to other chemotherapies [ 17 , 32 , 33 ]. Silver nanoparticle along with various plant extracts can have an immense potential to have anticancer activities and explored as a treatment for cancers [ 34 ].…”

Section: Introductionmentioning

confidence: 99%

Phytosynthesis of silver nanoparticles using aqueous sandalwood (Santalum album L.) leaf extract: Divergent effects of SW-AgNPs on proliferating plant and cancer cells

Gowda,

T. C.,

Anil

et al. 2024

PLoS ONE

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The biogenic approach for the synthesis of metal nanoparticles provides an efficient eco-friendly alternative to chemical synthesis. This study presents a novel route for the biosynthesis of silver nanoparticles using aqueous sandalwood (SW) leaf extract as a source of reducing and capping agents under mild, room temperature synthesis conditions. The bioreduction of Ag+ to Ago nanoparticles (SW-AgNPs) was accompanied by the appearance of brown color, with surface plasmon resonance peak at 340-360 nm. SEM, TEM and AFM imaging confirm SW-AgNP’s spherical shape with size range of 10-32 nm. DLS indicates a hydrodynamic size of 49.53 nm with predominant negative Zeta potential, which can contribute to the stability of the nanoparticles. FTIR analysis indicates involvement of sandalwood leaf derived polyphenols, proteins and lipids in the reduction and capping of SW-AgNPs. XRD determines the face-centered-cubic crystalline structure of SW-AgNPs, which is a key factor affecting biological functions of nanoparticles. This study is novel in using cell culture methodologies to evaluate effects of SW-AgNPs on proliferating cells originating from plants and human cancer. Exposure of groundnut calli cells to SW-AgNPs, resulted in enhanced proliferation leading to over 70% higher calli biomass over control, enhanced defense enzyme activities, and secretion of metabolites implicated in biotic stress resistance (Crotonyl isothiocyanate, Butyrolactone, 2-Hydroxy-gamma-butyrolactone, Maltol) and plant cell proliferation (dl-Threitol). MTT and NRU were performed to determine the cytotoxicity of nanoparticles on human cervical cancer cells. SW-AgNPs specifically inhibited cervical cell lines SiHa (IC50–2.65 ppm) and CaSki (IC50–9.49 ppm), indicating potential use in cancer treatment. The opposing effect of SW-AgNPs on cell proliferation of plant calli (enhanced cell proliferation) and human cancer cell lines (inhibition) are both beneficial and point to potential safe application of SW-AgNPs in plant cell culture, agriculture and in cancer treatment.

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“…Photothermal therapy (PTT), a treatment in which nanostructures are used, induces drug release or damages tumor cells with the heat produced by nanostructures under NIR laser irradiation [ 17 – 18 ]. Compared to traditional treatments, photothermal therapy allows for increased drug release and is less cytotoxic to healthy tissues [ 19 ]. It is a minimally invasive technique that offers the advantage of rapid recovery [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

Özcan,

Hazar Yoruç

2024

Beilstein J. Nanotechnol.

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In this study, a multifunctional therapeutic agent combining chemotherapy and photothermal therapy on a single platform has been developed in the form of vinorelbine-loaded polydopamine-coated iron oxide nanoparticles. Vinorelbine (VNB) is loaded on the surface of iron oxide nanoparticles produced by a solvothermal technique after coating with polydopamine (PDA) with varying weight ratios as a result of dopamine polymerisation and covalent bonding of thiol-polyethylene glycol (SH-PEG). The VNB/PDA/Fe3O4 nanoparticles have a saturation magnetisation value of 60.40 emu/g in vibrating sample magnetometry, which proves their magnetisation. Vinorelbine, which is used as an effective cancer therapy agent, is included in the nanocomposite structure, and in vitro drug release studies under different pH conditions (pH 5.5 and 7.4) and photothermal activity at 808 nm NIR laser irradiation are investigated. The comprehensive integration of precise multifunctional nanoparticles design, magnetic response, and controlled drug release with photothermal effect brings a different perspective to advanced cancer treatment research.

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Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect

Cited by 58 publications

References 60 publications

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Phytosynthesis of silver nanoparticles using aqueous sandalwood (Santalum album L.) leaf extract: Divergent effects of SW-AgNPs on proliferating plant and cancer cells

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

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