Iodine, copper, zinc, selenium and molybdenum levels in children aged between 6 and 12 years in the rural area with iodine deficiency and in the city center without iodine deficiency in Hatay

Abstract

Aim: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiency which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). Material and Methods:This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanışma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. Results:Iodine deficiency was found with a severe (5%), moderate (18.4%) and mild degree (43%), respectively in the village of Tanışma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p<0.001). A significant correlation was found between the levels of iodine, selenium, zinc and molybdenum (p<0.05). A moderately positive correlation was found between iodine and selenium (p<0.001). A moderately positive correlation was found between iodine and zinc levels (p<0.001) and a weak correlation was found between iodine and molybdenum (p<0.01). No significant correlation was found between iodine level and copper level (p>0.05).Conclusions: Selenium and zinc deficiency may accompany iodine deficiency. Selenium and zinc deficiency should be considered in individuals who are found to have iodine deficiency especially in endemic goitre regions. (Türk Ped Arş 2014; 49: 111-6)

Effects of Imbalance in Trace Element on Thyroid Gland from Moroccan Children

“…Different results were observed for Zn, Se, and I where the mean concentration in goitrous children was found to be lower than those in non-goitrous children. These results corroborate with several authors [4,39].…”

“…However, recent studies have shown that there are other goitrogen elements such as selenium and zinc [39,41].…”

Changes in the Serum Levels of Trace Elements Before and After the Operation in Thyroid Cancer Patients

“…Measurements conducted immediately after the operation also showed lower serum zinc and The differences between different superscripted letters in the same column are statistically significant (p < 0.05) Table 2 Pre-operative serum element levels of the cases Groups The differences between different superscripted letters in the same column are statistically significant (p < 0.05) Table 4 Post-operative serum element levels of the cases Groups selenium values than the control groups. There are several studies showing a correlation between zinc defect and thyroid hormone levels [16,19,20]. Zinc is an indispensable element in the functioning of 1,5′-deiodinase, which is necessary for the conversion of T 4 to T 3 [6].…”

Evaluation of nutritional status in children with amblyopia

“…Molybdenum deficiency is typically considered a metabolic disease and is characterized by a defect in psychomotor functioning. A correlation has been found between molybdenum and both selenium and iodine (21) . As a component of both tri-iodothyronine (T3) and tetra-iodothyronine (T4) thyroid hormones, iodine is critical for normal thyroid function, and selenium is a cofactor for thyroperoxidase, an enzyme catalyzing the production of these hormones in the thyroid gland.…”