Ion release and recharge from a fissure sealant containing amorphous calcium phosphate

Memarpour, Mahtab; Baghdadabadi, Neda Afzali; Rafiee, Azade; Vossoughi, Mehrdad

doi:10.1371/journal.pone.0241272

Cited by 10 publications

(4 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Probably, it was necessary to add a recharging solution during the pH cycle. Several studies advocated the use of such a solution to increase the pooling of ions [ 29 ]. This would have facilitated their uptake by the sealant to recharge it with ions.…”

Section: Discussionmentioning

confidence: 99%

Effect of a bioactive pit and fissure sealant on demineralized human enamel: in vitro study

Salma

AbdElfatah

2022

BMC Oral Health

View full text Add to dashboard Cite

Background Incorporation of bioactive agent into pit and fissure sealant would halt demineralization and promote further remineralization. The aim was to assess the effect of bioactive and fluoride fissure sealants on calcium and phosphate content and surface topography of artificially demineralized enamel in young permanent teeth. Methods 30 sound extracted premolars free from cracks or any developmental anomalies were used. They were divided into group I bioactive fissure sealant, group II fluoride fissure sealant and group III no material applied. Each tooth was divided into halves in a buccolingual direction and evaluated by energy dispersive X-ray spectrometer (EDX) at baseline, demineralization and after applying the material. Another set of 7 sound extracted premolars was evaluated by scanning electron microscopy (SEM) at the same phases. Results EDX showed that regaining calcium to demineralized enamel was significantly higher with bioactive sealant than either fluoride or the control group. SEM revealed minerals deposits with formation of distinct white zone at tooth/sealant interface for both pit and fissure sealant groups. Whereas no white zone formation was detected in control group. Conclusions Incorporating bioactive material into pit and fissure sealant through microcapsules provided better results than incorporating fluoride by enhancing the biological process of remineralization. Clinical relevance: The more use of bioactive pit and fissure sealant would maintain the occlusal surfaces as sound structures and decrease the need for operative procedures to restore teeth cavitation.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of a bioactive pit and fissure sealant on demineralized human enamel: in vitro study

Salma

AbdElfatah

2022

BMC Oral Health

View full text Add to dashboard Cite

show abstract

“…Amorphous calcium phosphate (ACP) is also added to dental materials in order to promote enamel remineralization and/or inhibit demineralization [90][91][92]. Release of calcium and phosphate ions from a fissure sealant containing ACP and re-release capacity of these ions when charged with a solution containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) are mechanisms applied in caries prevention [93]. Some surface pre-reacted glass ionomer sealants recently introduced to the market also show promising effects in the aspect of remineralization [94].…”

Section: Discussionmentioning

confidence: 99%

Brief Narrative Review on Commercial Dental Sealants—Comparison with Respect to Their Composition and Potential Modifications

Piszko,

Lubojański

et al. 2023

Materials

View full text Add to dashboard Cite

The scope of this paper is to compare different dental sealants and flow materials indicated for sealing pits and fissures considering their chemical formula. The narrative review aims to address the following questions: What is the essence of different dental sealants’ activity, how does their chemical formula affect their mechanisms of caries prevention, and what makes a dental sealant efficient mean of caries prevention? Another vital issue is whether the sealants that contain fluoride, or any other additions, have potentially increased antimicrobial properties. An electronic search of the PubMed, Cochrane, Web of Science, and Scopus databases was performed. The following keywords were used: (dental sealants) AND (chemical composition). Additionally, information about composition and indications for clinical use provided by manufacturers were utilized. All of the considered materials are indicated for use both in permanent and primary dentition for sealing fissures, pits, and foramina caeca. The selection of suitable material should be made individually and adjusted to conditions of the sealing procedure and patient’s needs. Cariostatic mechanisms increasing sealants’ effectiveness such as fluoride release are desired in modern dentistry appreciating preventive approach. The review aims are to find crucial elements of sealants’ composition which affect their cariostatic mechanisms.

show abstract

“…Clinpro™ FS releases a limited amount of fluoride ions and these ions cannot penetrate deeply. ACP has a higher mineral content than the fluoride sealant and leads to hydroxyapatite formation 16 , 31 – 34 . These factors might decrease %REMH in the ACP sealant groups after pH-cycling.…”

Section: Discussionmentioning

confidence: 99%

Penetration ability and microhardness of infiltrant resin and two pit and fissure sealants in primary teeth with early enamel lesions

Memarpour

Abedinzade

Rafiee

et al. 2022

Sci Rep

Self Cite

View full text Add to dashboard Cite

To determine the penetration depth and enamel microhardness (EMH) of an infiltrant resin and two fissure sealants in primary teeth with early enamel lesions. We randomly divided 174 sound teeth into six groups (n = 29): (1) phosphoric acid (PA) + Clinpro, (2) PA + Aegis, (3) Icon, (4) hydrochloric acid (HCl) + Clinpro, (5) HCl + Aegis, and (6) control. Percentage penetration (%PP) was analyzed by confocal laser scanning microscopy (n = 15). EMH was measured (n = 12), and the percentage of EMH recovery (%REMH) was calculated. Twelve samples were examined under a scanning electron microscope (SEM). All data were analyzed with the Kruskal–Wallis and one-way ANOVA tests (p < 0.05). Groups 3 and 4 showed the highest %PP (all, p < 0.05). Icon application led to significantly higher %REMH compared to the others (p < 0.05). Groups 2 and 5 showed the lowest reduction in %REMH after pH-cycling. Application of Icon and Clinpro with HCl pretreatment showed the greatest %PP. pH-cycling led to a decrease in %REMH for all of the materials, although this effect was lower in teeth treated with Aegis.

show abstract

Ion release and recharge from a fissure sealant containing amorphous calcium phosphate

Cited by 10 publications

References 42 publications

Effect of a bioactive pit and fissure sealant on demineralized human enamel: in vitro study

Effect of a bioactive pit and fissure sealant on demineralized human enamel: in vitro study

Brief Narrative Review on Commercial Dental Sealants—Comparison with Respect to Their Composition and Potential Modifications

Penetration ability and microhardness of infiltrant resin and two pit and fissure sealants in primary teeth with early enamel lesions

Contact Info

Product

Resources

About