1980
DOI: 10.1021/ac50061a058
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Ion-selective electrode for the determination of phencyclidine

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1980
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Cited by 35 publications
(8 citation statements)
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“…The extrinsic CD spectrum for PCP provides a novel way to qualitatively identify the compound (11). Although the calculation of K for PCP-sugar complexation is simpler, because [0]pcp -0, the calculation is frustrated by the fact that higher drug concentrations are required to enhance the small induced signal.…”
Section: Resultsmentioning
confidence: 99%
“…The extrinsic CD spectrum for PCP provides a novel way to qualitatively identify the compound (11). Although the calculation of K for PCP-sugar complexation is simpler, because [0]pcp -0, the calculation is frustrated by the fact that higher drug concentrations are required to enhance the small induced signal.…”
Section: Resultsmentioning
confidence: 99%
“…The sensor described here is reminiscent of much earlier work on ion-selective electrodes, potentiometric sensors, for hydrophobic drug molecules [55,56]. Both sensors use a hydrophobic membrane with fixed negative charge to extract hydrophobic cations into the membrane.…”
Section: Discussionmentioning
confidence: 99%
“…Investigation of an ion-selective electrode for I indicates that potentiometric analysis may provide adequate specificity for the parent drug (11). The reported sensitivity of this electrode is poor compared with radioimmunoassay or gas chromatographic (GC) methods.…”
mentioning
confidence: 99%