Ionic liquid as green solvent for the synthesis of α-terpineol from α-pinene

Aguilar-Elguézabal, A.; Torre-Sáenz, L. De la; Román-Aguirre, Manuel; Álvarez‐Contreras, Lorena

doi:10.1016/j.scp.2019.100207

Cited by 9 publications

(3 citation statements)

References 12 publications

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“…Acidic ionic liquid has been seen as an attractive alternative to traditional organic acids because of higher performance through their cations and better selectivity through their anions. Furthermore, ionic liquids eliminate the need for reaction solvents 56 and typically offer easier product purification. In addition, the ionic liquids are recyclable and are environmentally friendly.…”

Section: Pinene In the Synthesis Of Key Intermediates And Other Small...mentioning

confidence: 99%

The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance

Nyamwihura

Ogungbe

2022

RSC Adv.

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Section: Pinene In the Synthesis Of Key Intermediates And Other Small...mentioning

confidence: 99%

The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance

Nyamwihura

Ogungbe

2022

RSC Adv.

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“…ILs are also classified on the basis of their properties and their applications, such as task-specific ILs, supported ILs, chiral ILs, protic ILs, bio ILs, polarizable ILs, metal salt ILs, switchable-polarity solvents and deep eutectic solvents [ 6 , 7 ]. ILs are regarded as green solvents because of their recyclability and the potential to replace volatile organic solvents [ 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Study on the Effectiveness of Simultaneous Recovery and Concentration of 1-Ethyl-3-methylimidazolium Chloride Ionic Liquid by Electrodialysis with Heterogeneous Ion-Exchange Membranes

Babilas

Kowalik-Klimczak

Dydo

2021

IJMS

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Due to the extensive range of ionic liquids (ILs) used in industry, an efficient recovery method is needed. In this study, the effectiveness of a simultaneous concentration and recovery method was investigated for 1-ethyl-3-methylimidazolium chloride ([Emim]Cl), an IL that was recovered using electrodialysis (ED). The optimal operational parameters for electrodialytic recovery were determined empirically. The variables that were investigated included the concentration of IL, applied voltage, linear flow velocity and the diluate-to-concentrate volume ratio. The recovery of [Emim]Cl, the concentration degree, the [Emim]Cl flux across membranes, the current efficiency, as well as the energy consumption were determined. The results of the experiments confirmed that [Emim]Cl concentration and recovery can be achieved using ED. The highest ED efficiency was obtained when a 2 V electric potential per one membrane pair was applied, using a 2 cm/s linear flow velocity, and by adjusting to 0.2 M IL in the feed solution. By using ED, a 2.35-fold concentration of [Emim]Cl with a recovery of 90.4% could be achieved when the diluate-to-concentrate volume ratio was 2. On the other hand, a 3.35-fold concentration of [Emim]Cl with a recovery of 81.7% could be obtained when the diluate-to-concentrate volume ratio was increased to 5.

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“…Due to its floral, lilac-type, and sweet odor, α-TOH is one of the commonest ingredients used in the food industry as a flavoring agent, among other extensive applications 8 . As a result, its annually worldwide demand is ~330 tons 9 . Besides this, recent studies have been highlighting some novel biological functionalities for this monoterpenoid 10 , 11 , such as antitumor 12 ; antidepressant 13 ; anticonvulsant 14 ; anti-inflammatory 15 – 17 , antidiarrheal 18 ; antibacterial 19 and antifungal 20 .…”

Section: Introductionmentioning

confidence: 99%

Comprehensive study of α-terpineol-loaded oil-in-water (O/W) nanoemulsion: interfacial property, formulation, physical and chemical stability

et al. 2021

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In this study, the interfacial ability of α-terpineol (α-TOH) was reported, followed by its trapping into oil-in-water (O/W) nanoemulsion as active-ingredient and the long-term observation of this nanosystem influenced by the storage-time (410-days) and temperature (5, 25, 50 °C). The results indicated that the α-TOH can reduce the interfacial tension on the liquid-liquid interface (ΔG°m = −1.81 KJ mol−1; surface density = 8.19 × 10−6 mol m−2; polar head group area = 20.29 Å2), in the absence or presence of surfactant. The O/W nanoemulsion loaded with a high amount of α-TOH (90 mg mL−1; 9α-TOH-NE) into the oil phase was successfully formulated. Among the physical parameters, the mean droplet diameter (MDD) showed a great thermal dependence influenced by the storage-temperature, where the Ostwald ripening (OR) was identified as the main destabilizing phenomena that was taking place on 9α-TOH-NE at 5 and 25 °C along with time. Despite of the physical instability, the integrity of both nanoemulsion at 5 °C and 25 °C was fully preserved up to 410th day, displaying a homogeneous and comparable appearance by visual observation. On contrary, a non-thermal dependence was found for chemical stability, where over 88% of the initial amount of the α-TOH nanoemulsified remained in both 9α-TOH-NE at 5 and 25 °C, up to 410th day. Beyond the key data reported for α-TOH, the importance of this research relies on the long-term tracking of a nanostructured system which can be useful for scientific community as a model for a robust evaluation of nanoemulsion loaded with flavor oils.

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Ionic liquid as green solvent for the synthesis of α-terpineol from α-pinene

Cited by 9 publications

References 12 publications

The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance

The pinene scaffold: its occurrence, chemistry, synthetic utility, and pharmacological importance

Study on the Effectiveness of Simultaneous Recovery and Concentration of 1-Ethyl-3-methylimidazolium Chloride Ionic Liquid by Electrodialysis with Heterogeneous Ion-Exchange Membranes

Comprehensive study of α-terpineol-loaded oil-in-water (O/W) nanoemulsion: interfacial property, formulation, physical and chemical stability

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