Ionic Liquid–Hybrid Molecularly Imprinted Material–Filter Solid-Phase Extraction Coupled with HPLC for Determination of 6-Benzyladenine and 4-Chlorophenoxyacetic Acid in Bean Sprouts

Abstract

A new method involving ionic liquid-hybrid molecularly imprinted material-filter solid-phase extraction coupled to high-performance liquid chromatography (IL-HIM-FSPE-HPLC) was developed for the simultaneous isolation and determination of 6-benzyladenine (6-BA) and 4-chlorophenoxyacetic acid (4-CPA) in bean sprouts. Sample preconcentration was performed using a modified filter, with the new IL-HIM as the adsorbent, which shows double adsorption. The first adsorption involves special recognition of molecular imprinting, and the second involves ion exchange and electrostatic attraction caused by the ionic liquid. This method combines the advantages of ionic liquids, hybrid materials, and molecularly imprinted polymers and was successfully applied to determine 6-BA and 4-CPA in bean sprouts. The adsorption of 6-BA to IL-HIM is based on selective imprinted recognition, whereas the adsorption of 4-CPA is mainly dependent on ion-exchange interactions.

Protic Ionic Liquids as Efficient Solvents in Microwave-Assisted Extraction of Rhein and Emodin from Rheum palmatum L.

“…However, the remarkable deficiency of MAE is that the abundant volatile organic solvents used in the extraction process have detrimental effects on the environment and human health. Ionic liquids (ILs), constituting organic cations and inorganic anions with unique properties, such as a low melting temperature, high thermal stability, wide liquid phase range, and low vapor pressure, were used in the extraction of natural products [7,8,9]; however, 1,3-dialkylimidazolium-based ILs used in previous extraction processes entail a high cost [10,11,12]. Therefore, the use of green and economic solvents instead of hazardous solvents is one of the most important considerations during extraction [13,14].…”

Isolation of aristolochic acid I from herbal plant using molecular imprinted polymer composited ionic liquid‐based zeolitic imidazolate framework‐67

“…When the IL groups were modified on the surface of sorbents, they can provide a range of chemical bonds (hydrogen, ionic, π−π, et al.) to increase the interaction between sorbents and target compounds . Some studies have already applied IL to the modification of MOFs.…”

“…Ionic liquids (ILs) are well-known green reaction media with excellent chemical properties, such as hydrophilicity/hydrophobicity with different cations or anions, miscibility with several inorganic/organic solvents [18][19][20]. When the IL groups were modified on the surface of sorbents, they can provide a range of chemical bonds (hydrogen, ionic, π−π, et al) to increase the interaction between sorbents and target compounds [21]. Some studies have already applied IL to the modification of MOFs.…”

ZIF‐8@SiO2 core–shell microsphere extraction coupled with liquid chromatography and triple quadrupole tandem mass spectrometry for the quantitative analysis of four plant growth regulators in navel oranges

“…Therefore, it is necessary to further develop appropriate enrichment and cleanup steps before the analysis to obtain accurate analytical data. At present, the separation and enrichment of PGRs in food include liquid–liquid microextraction , SPE , matrix dispersion extraction , etc. In these methods, the disadvantage of LLE and SPE is that the reagent dosage is too large, the separation efficiency is low, and the operation is relatively tedious.…”