This study explores the transformative potential of fourth industrial revolution (called Industry 4.0) technologies in the context of poverty elimination, with a particular focus on Africa. Given the multidimensional nature of poverty, which spans economic, social, and environmental aspects, there is a critical need for innovative and sustainable solutions. This paper presents a comprehensive literature review to identify how recent advancements, such as artificial intelligence (AI), the Internet of Things (IoT), robotics, blockchain, big data, and 5G can be harnessed to address various facets of poverty. Drawing on insights from existing research and expert opinions, we propose a conceptual framework that integrates these technologies with strategic policy interventions, infrastructure development, and capacity building. The paper proposes a framework that illustrates the prerequisite requirements before adopting Industry 4.0 technologies in poverty elimination efforts. This framework aims to ensure that the benefits of technological innovations are accessible to the most vulnerable populations, thereby contributing to the broader goals of socioeconomic development and poverty reduction. The work shows that while Industry 4.0 presents a critical opportunity for sustainable development and poverty elimination in Africa, it needs to have essential capacities to optimize the use of observations, visualizations, and mindset management before or when adopting the first stage of Industry 4.0 solutions for poverty elimination.