2024
DOI: 10.1101/2024.06.15.24308935
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IP10 levels refine severity prognostication in COVID-19 and implicate causes of clinical deterioration: lessons for pandemic preparedness

Abhishek Das,
Jia Wei,
Duncan McKenzie
et al.

Abstract: SummaryBackgroundEmerging pandemics place immense strains on healthcare systems that may be ameliorated by rapid development of biomarkers whose measurements may predict disease severity and additionally inform about disease causation. Conspicuously, such routine measures rarely include immunological cytokines or chemokines, despite their contributions to host protection and immunopathology.MethodsMultiplex bead-array and ELISA-based serum cytokine and chemokine measurements, routinely employed clinical labora… Show more

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