Background: The projection of levels and composition of financial resources for the Healthcare expenditure (HCE) and relevant trends can provide a basis for future health financing reforms. This study aimed to project Iran’s healthcare expenditures by the sources of funds until 2030. Methods: The structural macro-econometric modeling in the Eviews 9 software was employed to simulate and project Iran’s (HCE) by the sources of funds (Government (GHCE), Social Security Organization (SOHCE), Out-of-Pocket Payments (OOP), and Prepaid Private Health Spending (PPHCE)). The behavioral equations were estimated by Autoregressive Distributed Lag (ARDL) approach. Results: If there is a 5%-increase in Iran’s oil revenues, the mean growth rate of GDP is about 2% until 2030. By this scenario, the Total HCE(THCE), GHCE, SOHCE, OOP, and PPHCE increases about 30.5%, 25.9%, 34.4%, 31.2%, and 33.9%, respectively. Therefore, the THCE as a percentage of the GDP(Gross Domestic Product)) will increase from 9.6% in 2016 to 10.7% in 2030. It is predicted that Iran’s THCE will cover 22.2%, 23.3%, 40%, and 14.5% by the government, Social Security Organization, households OOP, and other private sources, respectively, in 2030. Conclusion: Until 2030, Iran’s health expenditures will grow faster than the GDP, government revenues, and non-health spending. Despite the increase in GHCE and total government expenditure, the share of the GHCE from THCE has a decreasing trend. OOP payments remain among the major sources of financing for Iran’s HCE.