Iridium-catalysed thioether-directed regioselective cycloaddition of internal alkynes with azides

Abstract

We report herein a cationic iridium-catalysed thioether-directed alkyne-azide cycloaddition reaction. Diverse 2-alkynyl phenyl sulfides can undergo cycloaddition with different azides in a regioselective fashion. The reaction features high efficiency, short...