Iridoid Derivatives with Cytotoxic Activity from Pedicularis uliginosaBunge

Abstract

3), together with seven known analogues, were isolated from the 95 % EtOH extract of the whole plants of Pedicularis uliginosa BUNGE. Their structures were elucidated via extensive NMR spectroscopy and mass spectral data. In terms of inhibitory effects on human tumor cells, compounds 1, 2, 6, 7, and 8 exhibited better inhibitory activities against ACHN cells than the positive control (vinblastine).

Polyketides with α-glucosidase inhibitory and neuroprotective activities from Aspergillus versicolor associated with Pedicularis sylvatica

“…Pedicularis species are extensively used for treating fevers, rheumatism, hepatobiliary diseases, food poisoning, refining digestion and retaining vitality. 19 However, endophytic fungi associated with Pedicularis sylvatica L. have rarely been investigated. In continuing research into endophytic fungi, [20][21][22] a fungus associated with Pedicularis sylvatica produced four undescribed metabolites, aspeversins A-D (1, 2, 5 and 6), and four known compounds (3, 4, 7 and 8) (Fig.…”