Iridoid glucosides from Pentas lanceolata (Forssk.) Deflers growing on the Island of Sardinia

Abstract

The ethanolic extract of Pentas lanceolata (Forssk.) Deflers was investigated from a phytochemical point of view and in particular on the monoterpenoid glucosides content. Iridoid glucosides have a taxonomic relevance, e.g., asperuloside and its derivative are characteristic of the Rubioideae subfamily where this species is comprised. In the light of earliest phylogenetic molecular study which proposed to merge P. lanceolata in the Spermacoceae tribe, a phytochemical approach also becomes necessary for a correct classification of this species. A total of 12 compounds were identified in detail, ten of these are iridoid glucosides: asperuloside, asperulosidic acid, tudoside, E-uenfoside and Z-uenfoside previously identified in this genus; whereas, deacetyl-asperulosidic acid, ixoside, griselinoside, 6β,7β-epoxysplendoside were recognized here for the first time from P. lanceolata. Among the non-iridoidic compounds ursolic acid and d-xylose were identified

Isolation, identification of secondary metabolites from Salvia absconditiflora and evaluation of their antioxidative properties

“…Ursolic acid (1) was the first isolated compound during the chromatographic process. Its spectral data accorded with the literature (Venditti et al 2015). The second isolated compound was cirsimaritin (2).…”

New Coumarinyl Ethers in Daphne oleoides Schreb. Collected from Sardinia Island

“…For both these reasons, the wide variety of secondary metabolites and their bioactivities, the studies about the phytochemistry of this species are currently in the limelight. In this article, we report the phytochemical analysis of a sample of D. oleoides collected from a spontaneous population growing in Sardinia Island to verify if the isolated environment may have favored the development of a peculiar secondary metabolites pattern, as we already evidenced in other species growing in restricted areas and, in particular, in Sardinian territory . In fact, Sardinia, according to ‘Conservation International’ is part of the ten ‘mini‐Hotspots’ recognizable in the Mediterranean basin.…”

Secondary metabolites and biological activity of Pentas species: A minireview

“… Isolated compound Structure Species Extract/Organ Refs. Asperuloside 49 P. lanceolata MeOH/Aerial parts [32] MeOH/Colleter [18] EtOH/Entire plant [33] , [34] Asperulosidic acid 50 MeOH/Stem and leaves [32] EtOH/Entire plant [33] , [34] Tudoside 51 MeOH/Colleter [18] EtOH/Entire plant [28] 13 R - epi -Gaertneroside 52 P. lanceolate MeOH/Aerial parts [32] 13 R - epi -Epoxygaertneroside 53 EtOH/Entire plant [28] E -Uenfoside 54 Z -Uenfoside 55 MeOH/Aerial parts [32] EtOH/Entire plant [28] Loganin 56 MeOH/Colleter [18] Deacetyl-asperulosidic acid 57 EtOH/Entire plant [28] Ixoside 58 Griselinoside 59 6 β ,7 β -Epoxysplendoside 60 …”