Iron deficiency as a risk factor for simple febrile seizures-A case control study

Kumari, Pratima; Nair, M. K. C.; Nair, Salil; Kailas, Lalitha; Geetha, Selvaraj

doi:10.1007/s13312-012-0008-6

Cited by 49 publications

(19 citation statements)

References 13 publications

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“…In present study mean Hb, MCV and MCH was 8.92g%, 67.03 fl, 30.66 pg respectively which was significantly low in cases and compared to control. Kumari PL et al 24 and Naveed-ur-Rehmann et al 25 had results similar to our study. (Table-3) In present study, there was variation of the iron level with FS and FI group.…”

Section: Results and Observationssupporting

confidence: 91%

Iron Deficiency as a Risk Factor for First Febrile Seizure

Majumdhar¹,

K.R.²,

Venkatamurthy³

2013

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Estimation of Iron status in children with first febrile seizure (FFS). Iron status was evaluated by including Hemoglobin, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), Serum ferritin. MATERIALS AND METHODS: Study was conducted all children with first febrile seizures and febrile illnesses (FI) in Pediatrics Intensive Care Unit and Pediatrics Wards of Sri Adichunchanagiri Institute of Medical Sciences, B.G. Nagara from January 2010 to June 2011. The blood samples from the 50 children comprising the cases and 50 children comprising the controls constituted the material for the study. RESULTS : In the present study 58% cases were diagnosed as Iron Deficiency Anemia (IDA) with Febrile Seizure (FS); 18% controls were diagnosed as IDA with Febrile Illness. IDA was more frequent among children with FS than those with febrile illness alone. The result suggests that IDA may be a risk factor for FFS. Screening for IDA should be considered in children with FFS. CONCLUSION: Iron Deficiency Anemia is associated with the severity of a febrile illness, and more severe cases could be more likely to get seizures.

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Section: Results and Observationssupporting

confidence: 91%

Iron Deficiency as a Risk Factor for First Febrile Seizure

Majumdhar¹,

K.R.²,

Venkatamurthy³

2013

jemds

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“…Many authors point out that iron deficiency anemia in children is an important risk factor of the febrile seizures. This risk is higher in children with SFS between the ages of 6 months and 3 years (Derakhshanfar, Abaskhanian, Alimohammadi, & ModanlooKordi, 2012; Fallah, Tirandazi, Akhavan Karbasi, & Golestan, 2013; Kumari, Nair, Nair, Kailas, & Geetha, 2012; ur Rehman & Billoo, 2005; Sadeghzadeh, Khoshnevis Asl, & Mahboubi, 2012; Sherjil, us Saeed, Shehzad, & Amjad, 2010). A Sherjil et al.…”

Section: Discussionmentioning

confidence: 99%

The assessment of laboratory parameters in children with fever and febrile seizures

et al. 2017

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ObjectiveThe aim of the research paper was to assess selected laboratory results in children with fever without seizures and febrile seizure.Materials and MethodsThe paper presents an analysis of a group of 306 children aged 6 months – 5 years who were admitted with diagnosed fever without seizures and febrile seizures in Specialized Health Care Centre for Mother and Child in Poznan between 1st January 2008 and 31st December 2009. Out of the diagnostics procedures performed in children the following ones were taken into consideration: BCC and CRP.ResultsOf the analyzed group of 306 children, 59.48% were boys and 40.52% were girls. In the studied group 61.93% were boys and control group 56.15% were boys. Mean age of admitted children was 22 months. In the study group mean body temperature was 39.0°C and in the control group 38.6°C. A statistically significant difference was found between body temperature of study and control group (p = .005). The mean C‐reactive protein level in the study group was 15.73 mg/L and in the control group 58.20 mg/L. There was a statistically significant difference (p < .001). There was a statistically significant difference between the number of lymphocytes and neutrophils (p < .001). There was also a statistically significant difference between the number of hemoglobin, hematocrit and platelets.ConclusionsThe study showed that children with FS, had statistically significant higher neutrophils level compared to those with fever without seizures. The number of lymphocytes was lower in children with FS than in children with fever without seizures.

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“…These results have been repeated in other studies such as those carried out by Kumari et al . [12] Momen et al . [18] and Naveed al-Rahman and Billoo.…”

Section: Discussionmentioning

confidence: 99%

“…[11] Studies conducted on the role of iron deficiency in febrile convulsion have yielded completely conflicting results. In some of these studies, iron deficiency has been identified as a risk factor,[71213] while in others it has been stated that iron deficiency increases the threshold of neuron excitation and thus can play a protective role against febrile convulsion. [1415] Given these contradictory results, we decided to study the relationship between iron deficiency anemia and febrile convulsion in children hospitalized in Amir Kabir Hospital of Arak City.…”

Section: Introductionmentioning

confidence: 99%

The relationship between iron deficiency anemia and simple febrile convulsion in children

et al. 2014

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Background:Simple febrile convulsion is the most common disease of the nervous system in children. There are hypotheses that iron deficiency may affect febrile convulsion and the threshold of neuron excitation.Aims:This study was conducted with the objective of finding the effects of iron deficiency anemia on simple febrile convulsion episodes.Settings and Design:The study was conducted at AmirKabir Hospital of Arak Medical Sciences University, Arak, Iran. This is a case-control study.Materials and Methods:In this study, 382 children who were selected according to our inclusion and exclusion factors, were divided into two groups of case (febrile convulsion) and control (other factors causing fever) by their cause of hospitalization. After fever subsided, 5 ml blood sample was taken from each child and complete blood count and iron profile tests were performed.Statistical Analysis:The results were interpreted using descriptive statistics and independent t-test. Results: The prevalence of anemia in the group with febrile convulsion was significantly less than that in the control group: 22.5% of the children in the group with febrile convulsion and 34% in the control group exhibited anemia (P < 0.001). Moreover, the group with febrile convulsion had significantly higher blood indices, such as Hb, Hct, MCV, MCH, and MCHC, compared to the control group (P < 0.001).Conclusions:Iron deficiency can prevent febrile convulsion in children and probably increases the threshold of neuron excitation in fever.

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Iron deficiency as a risk factor for simple febrile seizures-A case control study

Abstract: Iron deficiency is a significant risk factor for simple febrile seizures in children of age group 6 months to 3 years.

Cited by 49 publications

References 13 publications

Iron Deficiency as a Risk Factor for First Febrile Seizure

Iron Deficiency as a Risk Factor for First Febrile Seizure

The assessment of laboratory parameters in children with fever and febrile seizures

The relationship between iron deficiency anemia and simple febrile convulsion in children

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