2023
DOI: 10.21203/rs.3.rs-3381469/v1
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Irregular word reading as a marker of cognitive and semantic decline in Alzheimer’s disease rather than an estimate of premorbid intellectual abilities.

Anna Marier,
Mahsa Dadar,
Florence Bouhali
et al.

Abstract: Background Irregular word reading has been used to estimate premorbid intelligence in Alzheimer’s disease (AD) dementia. However, reading models highlight the core influence of semantic abilities on irregular word reading, which shows early decline in AD. The general aim of this study is to determine whether irregular word reading is a valid estimate of premorbid intelligence, or a marker of cognitive and semantic decline in AD. Method 681 healthy controls (HC), 104 subjective cognitive decline, 290 early an… Show more

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