Irreversible Electroporation of the Femoral Neurovascular Bundle: Imaging and Histologic Evaluation in a Swine Model

Time-dependent impact of irreversible electroporation on pancreas, liver, blood vessels and nerves: a systematic review of experimental studies

“…Four studies on nerves were included using 84 animals [38,[46][47][48]. Animals used were either pigs [46][47][48] or rats [38].…”

“…Animals used were either pigs [46][47][48] or rats [38]. All animals survived the treatment and all ablations were successfully performed.…”

“…Gross pathology. Gross pathology of treated tissue showed well-demarcated, focal lesions [46][47][48]. One study reported lesions that were pale tan, firm, and contained numerous small (1 mm in diameter) hard white foci of calcification [39].…”

“…Most animals were able to put weight on as well as walk on the treated limb within 1-4 days (n = 20), but some animals were incapable of bearing any weight on the treated limb at this time after ablation (n = 2) [46][47][48]. …”

Electroporation: characteristics and therapeutic application of the method (a review)

“…Внутримышечная электропорация гена KGF со-провождалась стимуляцией пролиферации легочного эпи-телия и протекцией депрессии функции легких у мышей с моделированной эмфиземой [54]. Метод электропораци-онной терапии в экспериментальной и клинической меди-цине используется и по другим направлениям [51,[55][56][57][58].…”