Is adjuvant chemotherapy for bladder cancer safer in patients with an ileal conduit than a neobladder?

Manoharan, Murugesan; Reyes, Martha; Kava, Bruce R.; Singal, Rakesh; Kim, Sandy S.; Soloway, Mark S.

doi:10.1111/j.1464-410x.2005.05822.x

Cited by 9 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…29 However, the patient undergoing RC following neo-adjuvant chemo or radiotherapy might lead to some technical difficulties during surgery and postoperative period due to adhesions and bleeding tendency. 30,31 But with careful planning and use of modern techniques, those complications could be minimized. 20,21 In our study also three patients who had locally advanced tumor received neoadjuvant chemotherapy for downstaging of the tumor (Figure1).…”

Section: Bpkmchmentioning

confidence: 99%

Peri-Operative Morbidity and Outcomes of Radical Cystectomy- Institutional Experience of Single Center

et al. 2020

View full text Add to dashboard Cite

Introduction: The incidence of urinary bladder carcinoma increases distinctly with increasing age. Radicalcystectomy has been the gold standard for the treatment of patients with muscle-invasive bladder cancer or recurrent high-grade non-muscle invasive bladder cancer. Our study aimed to see the peri-operative morbidity and surgical outcomes of the patient who had undergone radical cystectomy in our low volume center. Methods: We retrospectively reviewed the inpatient charts as well as the outpatient records of 10 patients who had undergone radical cystectomy performed in our center for 9 years. A review of the literature on perioperativemorbidity of radical cystectomy was also done using the combination of keywords like mortality, complications, and outcomes of surgery. Results: Age of the patients ranged from 40-80 years. Eight of them were male and two were female. Painlesshematuria (70%) was the commonest presenting symptom, 80% of them were smokers. Three patients received neoadjuvant chemotherapy. Nine patients had radical cystectomy with an ileal conduit, whereas one patient hadradical cystectomy with orthotropic neo-bladder. In postoperative complications, five patients had Clavien-Dindograde I, three patients had grade II, one patient had grade IIIB and one patient had grade V complications. Two years of cancer-free survival was 90% and five years of cancer-free survival was 50%. Conclusions: Radical cystectomy with ileal conduit was still the choice of surgery in muscle-invasive and recurrent high-grade non-muscle invasive bladder cancer.

show abstract

Section: Bpkmchmentioning

confidence: 99%

Peri-Operative Morbidity and Outcomes of Radical Cystectomy- Institutional Experience of Single Center

et al. 2020

View full text Add to dashboard Cite

show abstract

“…This paper [1] was interesting; the relative contraindications to orthotopic bladder substitutes have been given as the presence of a diffuse carcinoma in situ (Cis) including the prostatic urethra, and high‐dose preoperative irradiation [2,3]. In this report, the authors stated that four patients had pathological stage 4 disease in the neobladder group.…”

mentioning

confidence: 99%