Is Complete Mesocolic Excision Technique Superior to Conventional Hemicolectomy Technique for Patients with Right-Sided Colon Cancer? Preliminary Findings from a Single-Center Retrospective Analysis

Tümay, Latif Volkan; Güner, Osman Serhat; BATI, İmam Bakır; Zorluoğlu, Abdullah

doi:10.4274/tjcd.galenos.2020.2020-8-4

Cited by 3 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One study followed patients for complications for 60 days [ 17 ], and another study for 90 days [ 21 ]. The timing for follow-up was not reported in 5 studies [ 15 , 16 , 19 , 22 , 24 ]. According to the meta-analysis, there was no difference in terms of the incidence of postoperative complications between the CME and the non-CME group (8 studies, 3899 patients, OR 1.04, 95% CI 0.89–1.22, p = 0.97, I 2 0%) (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Two studies reported an increase in 5-year OS for the CME group: 100% (CME) versus 89.49% (non-CME) ( p = 0.049) [ 15 ], and 89.4% (CME) versus 71.5% (non-CME) ( p = 0.011) [ 30 ]. Three studies reported no difference between the two groups for this outcome [ 17 , 22 , 24 ].…”

Section: Resultsmentioning

confidence: 99%

“…Five-year DFS was similar for both groups in two studies [ 15 , 22 ], but two studies reported results in favour of the CME group: 93.8% (CME) versus 78% (non-CME) ( p = 0.049) [ 30 ], and 89.9% (CME) versus 82.0% (non-CME) ( p = 0.00028) [ 17 ].…”

Section: Resultsmentioning

confidence: 99%

“…One study reported an improved incidence in distant recurrence, with 8% (CME) versus 24% (non-CME) ( p = 0.026) [ 23 ], whilst three studies no significant difference for this outcome [ 19 , 21 , 22 ].…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis

De Lange,

Davies,

Toso

et al. 2023

Tech Coloproctol

View full text Add to dashboard Cite

Purpose Complete mesocolic excision improves lymphadenectomy for right hemicolectomy and respects the embryological planes. However, its effect on cancer-free and overall survival is questioned. Therefore, we aimed to determine the potential benefits of the technique by performing a systematic review of the literature and meta-analysis of the available evidence. Methods Web of Science, PubMed/Medline, and Embase were searched on February 22, 2023. Original studies on short- and long-term oncological outcomes of adult patients undergoing right hemicolectomy with complete mesocolic excision as a treatment for primary colon cancer were considered for inclusion. Outcomes were extracted and pooled using a model with random effects. Results A total of 586 publications were identified through database searching, and 18 from citation searching. Exclusion of 552 articles left 24 articles for inclusion. Meta-analysis showed that complete mesocolic excision increased the lymph node harvest (5 studies, 1479 patients, MD 9.62, 95% CI 5.83–13.41, p > 0.0001, I2 84%), 5-year overall survival (5 studies, 2381 patients, OR 1.88, 95% CI 1.14–3.09, p = 0.01, I2 66%), 5-year disease-free survival (4 studies, 1376 patients, OR 2.21, 95% CI 1.51–3.23, p < 0.0001, I2 0%) and decreased the incidence of local recurrence (4 studies, 818 patients, OR 0.27, 95% CI 0.09–0.79, p = 0.02, I2 0%) when compared to standard right hemicolectomy. Perioperative morbidity was similar between the techniques (8 studies, 3899 patients, OR 1.04, 95% CI 0.89–1.22, p = 0.97, I2 0%). Conclusion Meta-analysis of observational and randomised studies showed that right hemicolectomy with complete mesocolic excision for primary right colon cancer improves oncologic results without increasing morbidity/mortality. These results need to be confirmed by high-quality evidence and randomised trials in selected patients to assess who may benefit from the procedure.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis

De Lange,

Davies,

Toso

et al. 2023

Tech Coloproctol

View full text Add to dashboard Cite

show abstract

Complete mesocolic excision (CME) impacts survival only for Stage III right-sided colon cancer: a systematic review and meta-analysis

Hayashi,

Passera,

Meroni

et al. 2024

Minimally Invasive Therapy & Allied Technologies

View full text Add to dashboard Cite

Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment

Ryu,

Kim,

et al. 2024

Ann Coloproctol

View full text Add to dashboard Cite

Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic methods, surgical techniques, and therapeutic agents.. The Korea Colon Cancer Multidisciplinary (KCCM) Committee intends to provide professionals who treat colon cancer with the most up-to-date, evidence-based practice guidelines to improve outcomes and help them make decisions that reflect their patients’ values and preferences. These guidelines have been established by consensus reached by the KCCM Guideline Committee based on a systematic literature review and evidence synthesis and by considering the national health insurance system in real clinical practice settings. Each recommendation is presented with a recommendation strength and level of evidence based on the consensus of the committee.

show abstract

Is Complete Mesocolic Excision Technique Superior to Conventional Hemicolectomy Technique for Patients with Right-Sided Colon Cancer? Preliminary Findings from a Single-Center Retrospective Analysis

Cited by 3 publications

References 0 publications

Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis

Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis

Complete mesocolic excision (CME) impacts survival only for Stage III right-sided colon cancer: a systematic review and meta-analysis

Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment

Contact Info

Product

Resources

About