Is delivery by cesarean section a risk factor for food allergy?

Birth by cesarean section, allergic rhinitis, and allergic sensitization among children with a parental history of atopy

“…Two studies of children followed only to the age of 2 years reported a positive association between cesarean delivery and sensitization to at least one aero-allergen 1133 . Eggesbø et al reported that cesarean delivery was associated with a threefold increase in the odds of parental report of food allergy (to egg, fish, or nuts) among 2,803 Norwegian children followed to age 2 years (95% CI for OR=1.4-7.3) 33 . Of relevance to our findings, the observed association between cesarean delivery and food allergy among Norwegian infants became much stronger after the analysis was stratified by maternal history of allergy.…”

Økt forekomst av keisersnitt – årsaker og konsekvenser

“…Keisersnitt er blitt forbundet med økt risiko for atopisk sykdom, spesielt matallergi (40) og astma (41,42). Dette kan muligens skyldes at barnet ikke kommer i kontakt med morens bakterieflora under forløsningen, siden kolonisering av tarmen påvirker utviklingen av immunsystemet (hygienehypotesen).…”

Infant antibiotic use and wheeze and asthma risk: a systematic review and meta-analysis

“…15 studies were excluded for the following reasons: antibiotic exposure was collected retrospectively (n54) [9][10][11][12]; no report on wheeze and/or asthma, but other allergic outcomes only (n56) [13][14][15][16][17][18]; no association measure for wheeze or asthma separately but an overall outcome called ''atopy'' which also included eczema and/or hay fever (n51) [19]; only prenatal antibiotic use reported (n53) [20][21][22]; and adult population (n51) [23].…”