At the long-wavelength approximation, E1 transitions are forbidden between isospin-zero states.Hence E1 radiative capture is strongly hindered in reactions involving N = Z nuclei but the E1 astrophysical S factor may remain comparable to, or larger than, the E2 one. Theoretical expressions of the isoscalar and isovector contributions to E1 capture are analyzed in microscopic and three-body approaches in the context of the α(d, γ) 6 Li reaction. The lowest non-vanishing terms of the operators are derived and the dominant contributions to matrix elements are discussed.The astrophysical S factor computed with some of these contributions in a three-body α + n + p model is in agreement with the recent low-energy experimental data of the LUNA collaboration.This confirms that a correct treatment of the isovector E1 transitions involving small isospin-one admixtures in the wave functions should be able to provide an explanation of the data without adjustable parameter. The exact-masses prescription which is often used to avoid the disappearance of the E1 matrix element in potential models is not founded at the microscopic level and should not be used for such reactions. The importance of capture components from an initial S scattering wave is also discussed. PACS numbers: 25.40.Lw,23.20.-g,21.10.Hw,21.60.Gx * dbaye@ulb.ac.be † tursune@inp.uz In some radiative-capture reactions between light nuclei, electric-dipole transitions are strongly suppressed [1]. This effect is due to an isospin selection rule: E1 transitions are isospin-forbidden in capture reactions involving N = Z nuclei [2].At the long-wavelength approximation, which is a good approximation for this type of reactions, the isoscalar part of the E1 operator vanishes and transitions take place via its isovector part. Matrix elements of isovector operators vanish between isospin-zero states. However, except for the deuteron, realistic wave functions of N = Z nuclei are not pure eigenstates of the isospin operator and E1 transitions are not exactly forbidden. Their strength may keep an order of magnitude similar to the strength of the usually much weaker E2 transitions. This effect is particularly spectacular for the 12 C(α, γ) 16 O reaction where the isospin-forbidden E1 component is enhanced by resonances (see references in Ref. [1]). Disentangling the E1 and E2 strengths is experimentally very difficult and the theoretical calculations of the E1 component are still quite uncertain. The role of E1 transitions is also complicated in other reactions of astrophysical interest such as d(d, γ) 4 He, 4 He(d, γ) 6 Li, and 16 O(α, γ) 20 Ne. It may also play some role in the triple α mechanism generating 12 C. An ab initio description of the two lightest cases is in principle possible at present. The astrophysical S factor of the d(d, γ) 4 He reaction has been computed with an ab initio calculation in Ref. [3]. The E1 component is mainly obtained from T = 1 isospin components in 4 He introduced by coupled p+ 3 H and n+ 3 He configurations. Its largest contribution reache...