Is It Really Safe to Discontinue Anticoagulant Treatment Before Ptosis Surgery From Serious Bleeding?

Abstract

The study aimed to evaluate the surgical effect of discontinuing anticoagulants preoperatively in patients with blepharoptosis. Patients were classified into two groups depending on anticoagulant treatment or otherwise. All patients taking anticoagulant discontinued with the treatment one week prior to surgery in accordance with our clinical guidelines. Preoperative and postoperative marginal reflex distance 1(MRD1) and ecchymosis grade were compared.Group 1 (anticoagulant treatment cessation) included 93 eyelids, and group 2 (control) included 98 eyelids. The preoperative MRD1 showed no significant difference between groups. Group 1 showed a significantly higher rate of severe ecchymosis (41.8 vs. 22.4%, p = 0.004) at 1 week of surgery as well as 'persistent ecchymosis (58.8 vs. 7.3%, p=0.000) postoperatively at 1 month. Postoperative MRD1 was significantly lower in group 1 at 1 week (p=0.019). However, the MRD1 and degree of improvement in lid height was not significantly different between the two groups (p = 0.499, p = 0.058) at 1 month postoperatively.