Is Laser En Bloc Resection Better than Conventional TURBT?

Sharma, Gopal

doi:10.1159/000508800

Cited by 4 publications

(1 citation statement)

References 3 publications

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“…Under the premise of ensuring the effect of anesthesia, this method has a small amount of anesthetic, which helps to reduce the perioperative stress response [ 6 ]. According to reports, the recurrence rate of bladder cancer is high, and about 1/3 of them have progressed, which seriously affects the effect of surgical treatment [ 7 , 8 ]. Western medicine routinely uses chemotherapy drugs to prevent the recurrence of bladder cancer after surgery; although it can reduce the risk of tumor recurrence to a certain extent, the overall effect is still unsatisfactory.…”

Section: Introductionmentioning

confidence: 99%

The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers

Zhang

Liu

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Objective. To explore the effects of traditional Chinese medicine nursing on general anesthesia combined with epidural anesthesia and electric resection to treat bladder cancer and its influence on tumor markers. Methods. A total of 160 patients with non-muscle-invasive bladder cancer who underwent general anesthesia combined with epidural anesthesia and resection were included in this study. The patients were divided into control group (n = 80) and study group (n = 80) according to the random number table method. The control group received hydroxycamptothecin bladder perfusion therapy, and the study group received traditional Chinese medicine nursing combined with hydroxycamptothecin bladder perfusion therapy. The clinical efficacy, three-year cumulative survival rate, and postoperative recurrence rate of the two groups of patients were detected. The levels of tumor markers including vascular endothelial growth factor (VECF) and bladder tumor antigen (BTA) before and after treatment were also tested. The immune function, inflammatory factor levels, and quality of life of the two groups before and after treatment were evaluated. Results. The total effective rate of the study group (83.75%) was significantly higher than that of the control group (58.75%). After treatment, the serum VEGF and BTA levels, inflammatory factors interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) levels of the two groups of patients decreased, and the decrease in the study group was more significant than that in the control group P < 0.05 . After treatment, the levels of CD3+, CD4+, and CD4+/CD8+ in the two groups increased P < 0.05 , and the increase in the study group was more significant than that in the control group P < 0.05 . After treatment, the CD8+ levels of the two groups of patients decreased P < 0.05 , and the decrease in the study group was more significant than that in the control group P < 0.05 . After treatment, the quality-of-life scores in both groups increased P < 0.05 , and the increase in the study group was even more significant P < 0.05 . Conclusion. Traditional Chinese medicine nursing has significant clinical effects on the treatment of bladder cancer with general anesthesia combined with epidural anesthesia and electric resection. It can more effectively prevent the risk of recurrence of bladder cancer after surgery, significantly improve the quality of life, improve immune system function, regulate the levels of VECF and BTA, effectively reduce the level of serum inflammatory factors, inhibit tumor progression, and reduce tumor viability.

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Section: Introductionmentioning

confidence: 99%

The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers

Zhang

Liu

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Development of a New Two-Arm Transurethral Surgical System for En Bloc Resection of Bladder Tumor: A Preclinical Study

Komai

Nakajima²,

Saito³

et al. 2023

Journal of Endourology

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En bloc resection of bladder tumors: challenges and unmet needs in 2022

Symeonidis

Chui

et al. 2022

Future Oncol.

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Non-muscle invasive bladder cancer accounts for the majority of new bladder cancer diagnoses, and endoscopic transurethral resection of bladder tumor (TURBT) represents the standard-of-care. Although a relatively safe and common procedure, TURBT is often hampered by the questionable quality of resection. The evolution of surgical techniques has brought en bloc resection of bladder tumor (ERBT) to the forefront. ERBT has emerged as an alternative to conventional TURBT, incorporating a more delicate en bloc sculpting and tumor excision, in contrast to ‘piecemeal’ resection by conventional TURBT. ERBT appears safe, feasible and effective with demonstrably higher rates of detrusor muscle in the pathologic specimen, all while providing better staging and obviating the need for a re-TURBT in selected patients. However, the method's adoption in the field is still limited. This review summarizes the recent evidence relevant to ERBT while further highlighting the technique's limitations and unmet needs.

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Is Laser En Bloc Resection Better than Conventional TURBT?

Cited by 4 publications

References 3 publications

The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers

The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers

Development of a New Two-Arm Transurethral Surgical System for En Bloc Resection of Bladder Tumor: A Preclinical Study

En bloc resection of bladder tumors: challenges and unmet needs in 2022

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