Is long COVID the next global health crisis?

Faghy, Mark A; Owen, Rebecca; Thomas, Callum; Yates, James; Ferraro, Francesco; Skipper, Lindsay; Barley-McMullen, Sarah; Brown, Darren; Arena, Ross; Ashton, Ruth

doi:10.7189/jogh.12.03067

Cited by 26 publications

(22 citation statements)

References 28 publications

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“…Today, the risk of becoming severely ill from COVID-19 is significantly lower than that seen in prior estimates because of protection provided by vaccination against SARS-CoV-2. Nevertheless, LC, which is defined by the persistence of COVID-19-related symptoms for weeks and months after the onset of infection with SARS-CoV-2, is predicted to be the next global health crisis with the growing burden on healthcare systems [ 14 , 15 ]. Subjects with persistent LC symptoms may have difficulty to perform daily activities and return to work that can negatively impact their quality of life and lead to great social as well as economic consequences [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Long-COVID-19 in Asymptomatic, Non-Hospitalized, and Hospitalized Populations: A Cross-Sectional Study

Bostancı

Gazi

Tosun

et al. 2023

JCM

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A substantial proportion of coronavirus disease 2019 (COVID-19) survivors continue to suffer from long-COVID-19 (LC) symptoms. Our study aimed to determine the risk factors for LC by using a patient population from Northern Cyprus. Subjects who were diagnosed with severe acute respiratory syndrome-2 (SARS-CoV-2) infection in our university hospital were invited and asked to fill in an online questionnaire. Data from 296 survivors who had recovered from COVID-19 infection at least 28 days prior the study was used in the statistical analysis. For determination of risk factors for “ongoing symptomatic COVID-19 (OSC)” and “Post-COVID-19 (PSC)” syndromes, the patient population was further divided into group 1 (Gr1) and group 2 (Gr2), that included survivors who were diagnosed with COVID-19 within 4-12 weeks and at least three months prior the study, respectively. The number of people with post-vaccination SARS-CoV-2 infection was 266 (89.9%). B.1.617.2 (Delta) (41.9%) was the most common SARS-CoV-2 variant responsible for the infections, followed by BA.1 (Omicron) (34.8%), B.1.1.7 (Alpha) (15.5%), and wild-type SARS-CoV-2 (7.8%). One-hundred-and-nineteen volunteers (40.2%) stated an increased frequency of COVID-19-related symptoms and experienced the symptoms in the week prior to the study. Of those, 81 (38.8%) and 38 (43.7%) were from Gr1 and Gr2 groups, respectively. Female gender, chronic illness, and symptomatic status at PCR testing were identified as risk factors for developing OSC syndrome, while only the latter showed a similar association with PSC symptoms. Our results also suggested that ongoing and persistent COVID-19-related symptoms are not influenced by the initial viral cycle threshold (Ct) values of the SARS-CoV-2, SARS-CoV-2 variant as well as vaccination status and type prior to COVID-19. Therefore, strategies other than vaccination are needed to combat the long-term effect of COVID-19, especially after symptomatic SARS-CoV-2 infection, and their possible economic burden on healthcare settings.

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Section: Discussionmentioning

confidence: 99%

Long-COVID-19 in Asymptomatic, Non-Hospitalized, and Hospitalized Populations: A Cross-Sectional Study

Bostancı

Gazi

Tosun

et al. 2023

JCM

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“…However, the risk of future variants of concern COVID-19 and future new pandemics is inevitable, posing a sustained challenge to global health. 71 The very nature of the elite sports will continue to change creating new working environments for sport scientists and medics. Therefore, we must take proactive steps to review recent reactive approaches and make considered and informed strategies that manage athlete physical, mental, and emotional wellbeing when future health threats are realized.…”

Section: Sports Cardiology and Covid-19mentioning

confidence: 99%

COVID-19 and elite sport: Cardiovascular implications and return-to-play

Faghy¹,

Ashton²,

Parizher³

et al. 2023

Progress in Cardiovascular Diseases

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“…With reports suggesting more than 100 million confirmed cases worldwide, Long COVID may arguably be the next global health crisis that will persist due to a lengthy disease course, lack of effective treatments, ongoing transmission, and additional co-morbid conditions along with their toll on physical, behavioral, cognitive, social, and economic burdens. 18 …”

mentioning

confidence: 99%