Is Low-Dose Ketamine an Effective Alternative to Opioids for Acute Pain?

Kirschner, Jonathan; Hunter, Benton R.

doi:10.1016/j.annemergmed.2018.11.001

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B) Hydromorphone1

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2020

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“…[24]. Unlike opioid analgesic medications that function by activating Mu receptors and are known agonists, low dose ketamine has a very low rate of adverse effects on the respiratory drive caused by over-sedation [9] [21] [24]. The characteristics of the molecular compound of ketamine and the low rate of adverse effects in non-dissociative dosing make ketamine the deal option for treatment of many types of pain.…”

Section: B) Hydromorphonementioning

confidence: 99%

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Low Dose Ketamine Used for Acute Pain Management in the Emergency Department

Kestenian¹,

Gantioque²,

Snyder³

2020

OJEM

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The use of opioid analgesics has created an opioid addiction epidemic in the United States and around the world. One of the main responsibilities of the emergency department is to address acute pain. In this paper we examine the use of low dose ketamine as a safe substitute for opioid analgesics. Types of pain are identified using prior established taxonomy, followed by discussing types of management and treatments. The opioid epidemic and its societal implications are considered. We also examine the side effects of ketamine and the use of ketamine as an adjunct to analgesics used for pain control. Recommendations and considerations for the use of ketamine are suggested, and a low dose ketamine administration sample hospital policy is reviewed.

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Section: B) Hydromorphonementioning

confidence: 99%

“…As an unintended consequence, the amount of lives lost constitutes a public health crisis. A review of literature identifies the evidence of the efficacy and safety of using low dose ketamine as an alternative to opioid analgesics [6] [7] [8] [9].…”

Section: Introductionmentioning

confidence: 99%