Is Muscle MELD a More Promising Predictor for Mortality After Living Donor Liver Transplantation?

Badawy, Amr; Kaido, Toshimi; Hamaguchi, Yuhei; Anazawa, Takayuki; Yagi, Shintaro; Fukumitsu, Ken; Kamo, Naoko; Okajima, Hideaki; Üemoto, Shinji

doi:10.1177/1526924818781571

Cited by 3 publications

(1 citation statement)

References 31 publications

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“…However, the APACHE score is impractical due to the large number of variables to be evaluated for liver disease and transplantation. Therefore, the tendency to research and develop the MELD score after LT and studies in this direction have increased [8,9].…”

Section: Introductionmentioning

confidence: 99%

The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients’ 30-day mortality after liver transplantation

Bayrak¹,

Gürkök²,

Aydemir³

et al. 2022

ceh

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Aim of the study:To investigate the disease-specific score and improve the existing scores to better determine the prognosis of patients after liver transplantation (LT). For this purpose, we evaluated the relationship of prognostic scores with 30-day mortality after LT. In addition, we planned to investigate whether the mean platelet volume/platelet count (MPR) would contribute to score improvement. Material and methods: A total of 178 adult patients admitted to the intensive care unit after LT in our hospital between 2011 and 2019 were retrospectively analyzed. Model for end-stage liver disease-sodium (MELDNa), Child-Turcotte-Pugh (CTP) score, and MPR values were compared in patients with and without 30-day mortality who underwent LT. Logistic regression analysis was performed to determine the predictive factors for mortality. A model was created with multivariate analysis. Results: Our study included 135 (75.8%) male and 43 (24.2%) female patients. There was a significant difference in the postLT-MELDNa score in the evaluation between those with and without mortality (p < 0.001). Age, postLT-MELDNa and CTP score were found to be significant in terms of the prediction of 30-day mortality in the univariate analysis (p < 0.05). mean platelet volume (MPV) and MPR were not significant in univariate analysis. Multivariate analysis revealed a model in which age and postLT-MELDNa were significant. Conclusions: In our study, postLT-MELDNa predicted 30-day mortality and was much more effective in predicting mortality when evaluated with age. The MELDNa score, which is currently used in the prognosis of candidates awaiting LT, may be useful for the prognosis of patients after LT in intensive care units.

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Section: Introductionmentioning

confidence: 99%

The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients’ 30-day mortality after liver transplantation

Bayrak¹,

Gürkök²,

Aydemir³

et al. 2022

ceh

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Which recipient pretransplant factors, such as MELD, renal function, sarcopenia, and recent sepsis influence suitability for and outcome after living donor liver transplantation? A systematic review of the literature and expert panel recommendations

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Spiro

Raptis

et al. 2022

Clinical Transplantation

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Combining Donor and Recipient Age With Preoperative MELD and UKELD Scores for Predicting Survival After Liver Transplantation

Kostakis¹,

Iype²,

Nasralla³

et al. 2021

Exp Clin Transplant

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Objectives: MELD, UKELD and D-MELD (donor age x MELD) have been assessed as scores for predicting survival after orthotopic liver transplantation (OLT), but with mediocre results. We introduced new indices based on preoperative MELD and UKELD scores, assessed their predictive ability concerning post-OLT survival, and compared it with that of the pre-existing scores. Methods: We included 1017 OLTs from deceased donors that were performed in our department between 2008 (the year UKELD was introduced) and 2019. Data were collected about donor and recipient characteristics (including MELD and UKELD scores), and transplant characteristics and outcomes. The following scores were calculated: D-MELD, D-UKELD (donor age x UKELD), DR-MELD [(donor age+recipient age)xMELD], DR-UKELD [(donor age+recipient age)xUKELD]. Results: No score had predictive value concerning graft survival. Regarding patient survival, DR-MELD and DR-UKELD provided the best results, but with a low accuracy. The highest accuracy was observed at 1 year post OLT

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Is Muscle MELD a More Promising Predictor for Mortality After Living Donor Liver Transplantation?

Abstract: Muscle-MELD score is a simple and useful predictor of patient survival after LDLT which showed a better predictive performance than other available scores.

Cited by 3 publications

References 31 publications

The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients’ 30-day mortality after liver transplantation

The predictive value of MELDNa (model for end-stage liver disease-sodium) and mean platelet volume/platelet count for patients’ 30-day mortality after liver transplantation

Which recipient pretransplant factors, such as MELD, renal function, sarcopenia, and recent sepsis influence suitability for and outcome after living donor liver transplantation? A systematic review of the literature and expert panel recommendations

Combining Donor and Recipient Age With Preoperative MELD and UKELD Scores for Predicting Survival After Liver Transplantation

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