Is peripheral venovenous-arterial ECMO a feasible alternative to central cannulation for pediatric refractory septic shock?

Bichara, G.; Furlanetto, Beatriz Helena; Teixeira, L Gondim; Nardo, Matteo Di

doi:10.1007/s00134-019-05720-z

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…Cardiac failure associated with septic shock or cardiac arrest (ECPR) is also another ECMO indication in neonates [71]. Hospital survival in these groups is variable and ranges between 40 and 50% [18,74,75].…”

Section: Ecmo For Neonatal Cardiac Failurementioning

confidence: 99%

Neonatal respiratory and cardiac ECMO in Europe

et al. 2021

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Neonatal extracorporeal membrane oxygenation (ECMO) is a life-saving procedure for critically ill neonates suffering from a potentially reversible disease, causing severe cardiac and/or respiratory failure and refractory to maximal conventional management. Since the 1970s, technology, management, and clinical applications of neonatal ECMO have changed. Pulmonary diseases still represent the principal neonatal diagnosis, with an overall 74% survival rate, and up to one-third of cases are due to congenital diaphragmatic hernia. The overall survival rate in cardiac ECMO is lower, with congenital heart defect representing the main indication. This review provides an overview of the available evidence in the field of neonatal ECMO. We will address the changing epidemiology, basic principles, technologic advances in circuitry, and monitoring, and deliver a current multidisciplinary management framework, focusing on ECMO applications, complications, and long-term morbidities. Lastly, areas for further research will be highlighted. Conclusions : ECMO is a life support with a potential impact on long-term patients’ outcomes. In the next years, advances in knowledge, technology, and expertise may push neonatal ECMO boundaries towards more premature and increasingly complex infants, with the final aim to reduce the burden of ECMO-related complications and improve overall patients’ outcomes. What is Known: • ECMO is a life-saving option in newborns with refractory respiratory and/or cardiac failure. • The multidisciplinary ECMO management is challenging and may expose neonates to complications with an impact on long-term outcomes. What is New: • Advances in technology and biomaterials will improve neonatal ECMO management and, eventually, the long-term outcome of these complex patients. • Experimental models of artificial placenta and womb technology are under investigation and may provide clinical translation and future research opportunities.

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Section: Ecmo For Neonatal Cardiac Failurementioning

confidence: 99%

Neonatal respiratory and cardiac ECMO in Europe

et al. 2021

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“…VA ECMO has been proposed as a rescue therapy in neonates and children with refractory septic shock, most likely due to heart failure being the primary cause of shock. [ [71] , [72] , [73] , [74] , [75] ] In adults, several retrospective studies have shown that VA ECMO is feasible in patients with SCM who have left heart failure and cardiogenic shock. Kim et al.…”

Section: The Choice Of Ecmo Modementioning

confidence: 99%

Extracorporeal membrane oxygenation in adult patients with sepsis and septic shock: Why, how, when, and for whom

Zhang,

Xu,

Huang

et al. 2024

Journal of Intensive Medicine

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“…apy for pediatric RSS are analyzed in Table 1. Among them, seven [4,[8][9][10][11][12][13] are retrospective single-center studies, with a total of 144 cases analyzed; one is a prospective multicenter study, in which 70 patients (64 children and six neonates) from eight hospitals are observed. Currently, studies on ECMO for pediatric RSS treatment are mainly originated from Europe, North America, and Australia, with few covered in Asia.…”

Section: Current Status Of Treating Rss With Ecmomentioning

confidence: 99%

Extracorporeal membrane oxygenation for refractory septic shock in children

2024

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Children are susceptible to developing sepsis. Among its complications, septic shock is the most severe. Refractory septic shock (RSS) is defined as septic shock that is unresponsive to standard resuscitation. As the most severe complication of sepsis in children, refractory septic shock (RSS) is characterized by its rapid development and high mortality rate. In accordance with relevant guidelines and consensus, extracorporeal membrane oxygenation (ECMO) is recommended as a salvage therapy for the treatment of RSS in children. However, various controversies and difficulties still exists when ECMO is used to treat children with RSS. Thus, this review summarizes the current status, difficulties, and explorations of applying ECMO to the treatment of RSS in children.

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Is peripheral venovenous-arterial ECMO a feasible alternative to central cannulation for pediatric refractory septic shock?

Cited by 4 publications

References 5 publications

Neonatal respiratory and cardiac ECMO in Europe

Neonatal respiratory and cardiac ECMO in Europe

Extracorporeal membrane oxygenation in adult patients with sepsis and septic shock: Why, how, when, and for whom

Extracorporeal membrane oxygenation for refractory septic shock in children

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