Is sensorineural hearing loss related with thyroid metabolism disorders

Karakus, Canan Filiz; Altuntaş, Emine Elif; Kilicli, Fatih; Durmuş, Kasım; Hasbek, Zekiye

doi:10.4103/0971-7749.155310

Cited by 9 publications

(2 citation statements)

References 16 publications

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“…The prevalence of hypothyroidism, which is associated with type 2 diabetes and hearing loss, was higher in our study than in the literature, and this may explain the high prevalence of hearing loss observed in this study. 17 The presence of microvascular and macrovascular complications was associated with hearing loss in this cohort, which is in line with the findings of several studies, particularly in terms of neuropathy and nephropathy. Neuropathy may contribute directly to nerve damage in the cochlea.…”

Section: Discussionsupporting

confidence: 92%

Hearing loss among patients with type 2 diabetes mellitus: a cross-sectional study

Al‐Rubeaan¹,

Al-momani

AlGethami

et al. 2021

Ann Saudi Med

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BACKGROUND: Hearing loss is an underestimated comorbid condition in type 2 diabetes. OBJECTIVES: Investigate hearing loss as a comorbidity associated with type 2 diabetes mellitus and evaluate the factors associated with hearing loss. DESIGN: Cross-sectional. SETTING: Tertiary care center, diabetes clinic. PATIENTS AND METHODS: Patients with type 2 diabetes, aged 30 to 60 years, were randomly selected to participate. All patients underwent clinical ear examinations and were referred for full audiological evaluation. Otoacoustic emission was used to assess inner function, tympanometry to assess middle-ear function, and pure tone air/bone audiometry to assess hearing sensitivity. Risk factors for hearing loss were assessed by multivariate logistic regression. MAIN OUTCOME MEASURE: Frequency, severity and risk factors for hearing loss. SAMPLE SIZE: 157 RESULTS: Of the 157 patients, 77 had hearing loss in both ears (49.0%), 13 in the right ear only (8.3%), 14 in the left ear only (8.9%), and 53 (33.8%) had normal hearing. In the 181 ears with sensorineural hearing loss, 90 had mild loss (49.7%), 69 moderate loss (38.2%), 16 severe loss (8.8%) and 6 had profound loss (3.3%). Disabling hearing loss was observed in 46 (29%) patients. A higher frequency of hearing loss was present in patients with glycated hemoglobin levels ≥8%. In the multivariate logistic regression analysis, the most important factors associated with hearing loss were longer diabetes duration, poor glycemic control and the presence of hypertension. CONCLUSIONS: Hearing loss is an underestimated comorbid condition in type 2 diabetes that warrants frequent hearing assessments and management. Strict glycemic and hypertension control is essential for the minimization of the effects of diabetes on hearing sensitivity. LIMITATIONS: Small sample size, limited age window (30-60 years), which was chosen to eliminate the natural aging effect on hearing. Cross-sectional nature was not ideal for the assessment of causality. CONFLICT OF INTEREST: None.

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Section: Discussionsupporting

confidence: 92%

Hearing loss among patients with type 2 diabetes mellitus: a cross-sectional study

Al‐Rubeaan¹,

Al-momani

AlGethami

et al. 2021

Ann Saudi Med

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“…There have been several reports of hypothyroidism-induced rhabdomyolysis [8, 9, 11, 12], hypothyroidism-induced pericardial effusion [13, 14], and sensorineural hearing loss related to autoimmune thyroid disease [15–17] in recent decades. Zare-khormizi et al presented the case of a patient with massive pericardial effusion and rhabdomyolysis secondary to untreated severe hypothyroidism [18].…”

Section: Discussionmentioning

confidence: 99%

Untreated primary hypothyroidism with simultaneous rhabdomyolysis, pericardial effusion, and sudden sensorineural hearing loss: a case report

et al. 2019

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Background Hypothyroidism, one of the prevalent endocrine disorders worldwide, has a broad spectrum of clinical manifestations, from an asymptomatic condition to myxedema coma. Although the majority of patients with hypothyroidism have minor clinical symptoms, which are recovered with levothyroxine treatment, some patients occasionally do experience fatal complications. Here we report, for the first time, the case of a patient who had hypothyroidism with simultaneous occurrence of rhabdomyolysis with acute kidney injury, moderate pericardial effusion, and sudden sensorineural hearing loss. Case presentation A 57-year-old man with a previous history of dyslipidemia and untreated hypothyroidism was admitted to the hospital due to shortness of breath, lethargy, lower extremity discomfort, and unilateral hearing loss. Laboratory results revealed rhabdomyolysis with acute kidney injury and severe hypothyroidism. We detected cardiomegaly without lung parenchymal infiltration on chest radiography and moderate pericardial effusion on transthoracic echocardiography. We performed pure tone audiometry and identified profound unilateral sensorineural hearing loss. Aggressive fluid resuscitation, levothyroxine treatment, and systemic and intratympanic steroid therapy alleviated the patient’s severe hypothyroidism, rhabdomyolysis, and pericardial effusion; however, sensorineural hearing loss was not fully recovered. Conclusions Early recognition of life-threatening complications is important in patients with severe hypothyroidism to prevent adverse outcomes. This case suggests that hypothyroidism should be considered in patients who have rhabdomyolysis with acute kidney disease and pericardial effusion. Moreover, sudden sensorineural hearing loss should be kept in mind as a rare complication of hypothyroidism.

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Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

et al. 2018

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ObjectiveThe objective of this study was to examine the effect of hypothyroidism on hearing function in patients surgically treated for differentiated thyroid cancer and subsequently experienced hypothyroidism during preparation for follow up I-131 scintigraphy scan by either recombinant human thyroid stimulating hormone (rhTSH) treatment or thyroid hormone withdrawal (THW).MethodsA total of 55 patients undergoing I-131 scintigraphy scan following surgeries for differentiated thyroid cancer were included in the study, including 25 patients prepared by administration of recombinant TSH (rhTSH Group) and 30 patients by thyroid hormone withdrawal (THW Group).ResultsAir conduction thresholds at 1, 2 and 4 kHz for both ears were higher during hypothyroid period than during euthyroid period for patients in the THW group (p < 0.05) but not for patients in the rhTSH group.ConclusionSensorineural hearing loss was detected, especially at low frequencies, in patients with DTC after surgical treatment whose hormone replacement therapy was withdrawn but not in those receiving rhTSH. It is therefore preferred to use rhTSH when preparing for I-131 scintigraphy scan in patients at risk for hearing loss.

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Is sensorineural hearing loss related with thyroid metabolism disorders

Cited by 9 publications

References 16 publications

Hearing loss among patients with type 2 diabetes mellitus: a cross-sectional study

Hearing loss among patients with type 2 diabetes mellitus: a cross-sectional study

Untreated primary hypothyroidism with simultaneous rhabdomyolysis, pericardial effusion, and sudden sensorineural hearing loss: a case report

Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

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