“…1 limit PPIs to 2-week regimens and then only for the most Dr Inadomi and colleagues evaluated a step-down serious cases. been investigated before, the studies have typically While these results favour the use of PPIs as first-line considered the treatment of gastric ulcers, not GORD, therapy, prescription of these agents is tightly controlled commented Dr John Inadomi from the US Veteran's in Japan's healthcare system.…”