Is there any connection between heat inactivation of spectrin‐dependent ATPase and loss of smooth biconcave shape of red cells?

Mircevová, L; Kodı́ček, Milan; Marík, T

doi:10.1002/cbf.290010305

Cell Biochemistry & Function

1983

DOI: 10.1002/cbf.290010305

|View full text |Cite

Is there any connection between heat inactivation of spectrin‐dependent ATPase and loss of smooth biconcave shape of red cells?

L Mircevová¹,

Milan Kodı́ček²,

T Marík³

Abstract: Spectrin-dependent ATPase activity was measured in membranes from native human erythrocytes and erythrocytes heated for 20 min at different temperatures. This activity was found to decline when the erythrocytes were heated at 48 degrees C and higher. The break in ATPase activity corresponds to morphological changes in erythrocytes found by Crome and Mollison [Brit. J. Haematol. (1964) 10, 137]. The role of spectrin-dependent ATPase in erythrocyte shape maintenance is discussed.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1991

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Tellurite effect on ATPase activity of contractile membrane protein

Mircevová

Kodı́ček

1991

Cell Biochemistry & Function

View full text Add to dashboard Cite

The effect of tellurite on ATPase activity of the contractile membrane protein in human erythrocytes was studied. Tellurite, even at a concentration of 0.01 mM, inhibited 25 per cent of the saponin-stimulated ATPase activity of the contractile membrane protein; the inhibition increased with increasing tellurite concentration, and was reversible. On the other hand, in erythrocytes preincubated with tellurite, the ATPase activity of the membrane contractile protein, non-stimulated by saponin, increased, and the increase was further enhanced by washing the erythrocytes. The behaviour is analogous to the tellurite effect on erythrocyte morphology: incubation of erythrocytes with tellurite caused morphological changes which were more pronounced after removing the tellurite by washing. The complex effect of tellurite is discussed.

show abstract

Tellurite effect on ATPase activity of contractile membrane protein

Mircevová

Kodı́ček

1991

Cell Biochemistry & Function

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Is there any connection between heat inactivation of spectrin‐dependent ATPase and loss of smooth biconcave shape of red cells?

Cited by 1 publication

References 17 publications

Tellurite effect on ATPase activity of contractile membrane protein

Tellurite effect on ATPase activity of contractile membrane protein

Contact Info

Product

Resources

About