“…Recent studies suggest that the real pathogenesis of most cases with dementia is multifactorial and complex rather than a single pathology, and a combination of multiple processes such as DAT pathology, inflammation, Lewy bodies, and vascular lesions contribute to the cognitive decline with aging [23][24][25]. Therefore, in addition to the coincidental occurrence SS with other dementia and CNS SS with cognitive decline, a third clinical condition, SS as an exacerbating factor of other dementia, might be involved in the patients with SS.…”