Ischemic Priapism in a 12 Year Old Patient Associated With Coronavirus Disease 2019 (COVID-19): A Case Report

Brönimann, Stephan; Talhammer, Florian; Tonnhofer, Ursula; Shariat, Shahrokh F.; D’Andrea, David

doi:10.1016/j.urology.2022.01.022

Cited by 3 publications

(26 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 9 , 20 ] Of the 4 (26.7%) remaining cases, all were reported to have mild COVID-19 infection and did not require supplemental oxygen. [ 10 , 12 , 18 , 19 ]…”

Section: Resultsmentioning

confidence: 99%

“…Among the 10 cases in which cavernous blood gas was recorded, [ 6 , 8 – 14 , 17 , 18 ] the pH was <7.25 in 8 (80.0%) cases, [ 6 , 8 – 11 , 14 , 17 , 18 ] PaCO 2 was ≥60 mm Hg in 4 (40.0%), [ 6 , 8 , 10 , 17 ] and PaO 2 was <30.1 mm Hg in 2 (20.0%) cases. [ 8 , 9 ]…”

Section: Resultsmentioning

confidence: 99%

“…[ 19 ] Except for a single case that required a bilateral T-shunt (corpora-glandular) procedure, [ 12 ] a case requiring a caverno-cancellous shunt and posthectomy, [ 16 ] and another case that presented 3 days after the onset of priapism with established penile gangrene and required a partial penectomy, [ 20 ] the remaining 10 (66.7%) cases responded to standard therapy that included a combination of ice pack application, cavernosal aspiration/irrigation, and intracavernosal sympathomimetic injections. [ 6 , 8 – 11 , 13 – 15 , 17 , 18 ] With regard to the treatment of concomitant COVID-19, 4 cases required mechanical ventilation, [ 6 – 8 , 13 ] while anticoagulation therapy was administered to 8 (53.3%). [ 6 , 8 , 9 , 11 , 13 , 16 – 18 ]…”

Section: Resultsmentioning

confidence: 99%

“…[ 6 , 8 – 11 , 13 – 15 , 17 , 18 ] With regard to the treatment of concomitant COVID-19, 4 cases required mechanical ventilation, [ 6 – 8 , 13 ] while anticoagulation therapy was administered to 8 (53.3%). [ 6 , 8 , 9 , 11 , 13 , 16 – 18 ]…”

Section: Resultsmentioning

confidence: 99%

“…As COVID-19 has been associated with significantly higher mortality in the elderly, [ 35 ] age may also play a role. Although the majority of patients in this study were aged between 60 and 70 years, 4 patients were below the age of 40 years, [ 12 , 13 , 18 , 19 ] 3 of whom had mild COVID-19 infection, [ 12 , 18 , 19 ] and 2 were in the pediatric age group. [ 18 , 19 ] This suggests that, although older patients with COVID-19 are more prone to developing priapism, it may also occur in younger patients.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Coronavirus disease 2019 (COVID-19) and priapism: An unexplored association

et al. 2022

View full text Add to dashboard Cite

Background: Coronavirus disease 2019 (COVID-19) has an established impact on multiple organ systems, including the vascular and urogenital systems. Vascular effects may include venous thromboembolic disease, which could theoretically be a precursor to priapism—a urological emergency defined as an abnormal condition of prolonged penile erection lasting >4 hours. To better explore this association, we critically appraised all the published COVID-19 cases associated with priapism. Materials and methods: After PROSPERO registration ( CRD42021245257), a systematic search of Google Scholar, Scopus, Embase, Web of Science, PubMed, Cumulative Index to Nursing and Allied Health Literature, Global Index Medicus, and Cochrane Database of Systematic Reviews was performed using specific search terms. The following study metadata were extracted: age, requirement for respiratory support, cavernous blood gas findings, management of priapism, and patient outcomes. Results: Fifteen single-patient case reports were included in this review. Of these, all of the patients presented with ischemic priapism, 9 patients (60.0%) were >60 years of age, 4 (26.7%) reported more than a single episode of priapism, 11 (73.3%) presented with pneumonia, 8 (53.3%) required mechanical ventilation, D-dimer was elevated in 5 of the 6 (83.3%) patients in whom this was reported, and among the 13 patients in whom mortality was reported, 4 (30.8%) died. Conclusions: Early reports suggest a prognostic relationship between COVID-19 and coexisting priapism. However, owing to commonalities in their pathophysiology and the small dataset reported in the literature, the probable association between COVID-19 and priapism is still theoretical. Further research is needed to confirm this association.

show abstract

“…[ 9 , 20 ] Of the 4 (26.7%) remaining cases, all were reported to have mild COVID-19 infection and did not require supplemental oxygen. [ 10 , 12 , 18 , 19 ]…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Coronavirus disease 2019 (COVID-19) and priapism: An unexplored association

et al. 2022

View full text Add to dashboard Cite

show abstract

Priapism associated with COVID-19: a pediatric case

Çelebi¹,

Böncüoğlu²,

Düzgöl³

et al. 2022

Turk J Pediatr

View full text Add to dashboard Cite

Background. Urological involvement is rare in patients with coronavirus disease 2019 (COVID-19). Priapism, one of the urological involvements, was reported as one of the COVID-19 comorbidities in the elderly male patient group but has rarely been reported in the pediatric age group. Case. Herein, a previously healthy 8-year-old patient with COVID-19-associated priapism, which is rare in children, is presented. Conclusions. During the pandemic, in pediatric cases with priapism of unknown etiology, COVID-19 should be one of the diagnoses to be considered.

show abstract

Epididymitis, orchitis, and epididymo-orchitis associated with SARS-CoV-2 infection in pediatric patients: A systematic review

Inouye¹,

Baker²,

Vasquez³

2023

Front. Urol.

View full text Add to dashboard Cite

IntroductionEpididymitis, orchitis, and epididymo-orchitis (EO) are common disorders in pediatric patients which may be caused by infection, trauma, or inflammation. SARS-CoV-2 associated EO has been previously described, particularly in adults. However, no systematic reviews of these manifestations in pediatric patients yet exist. We present a systematic literature review of epididymitis, orchitis, and EO associated with SARS-CoV-2 in pediatric patients to shed light on these relatively rare, yet potentially severe, conditions to understand presentation, course of illness, management options, and outcomes.Materials and MethodsFollowing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic review was performed using specified key terms to search PubMed, Cumulative Index to Nursing and Allied Health Literature, Web of Science, and Embase. Articles were independently screened by two reviewers. Manuscripts with detailed descriptions of SARS-CoV-2 associated epididymitis, orchitis, or EO in pediatric patients were included. Exclusion criteria included: no clear diagnosis of the target diseases and no detailed clinical course described. Quality and bias were assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Case Reports.Results60 records were initially identified, with 6 case reports included in the systematic review. All 6 patients included presented with fever and genitourinary symptoms. Four patients were also diagnosed with multisystem inflammatory syndrome in children (MIS-C). One patient underwent surgical exploration for presumed testicular torsion, though intraoperatively there was no evidence of torsion. All patients recovered without documented long-term sequelae.DiscussionWhile observational studies are prone to bias, this systematic review suggests that epididymitis, orchitis, and EO are significant manifestations of SARS-CoV-2 that may mimic urologic emergencies (i.e., testicular torsion). Providers should suspect these conditions in pediatric COVID-19 patients with scrotal symptoms, particularly with associated MIS-C. The long-term genitourinary sequelae of SARS-CoV-2 should be investigated, including the effects on pediatric patients undergoing reproductive development.

show abstract

Ischemic Priapism in a 12 Year Old Patient Associated With Coronavirus Disease 2019 (COVID-19): A Case Report

Cited by 3 publications

References 14 publications

Coronavirus disease 2019 (COVID-19) and priapism: An unexplored association

Coronavirus disease 2019 (COVID-19) and priapism: An unexplored association

Priapism associated with COVID-19: a pediatric case

Epididymitis, orchitis, and epididymo-orchitis associated with SARS-CoV-2 infection in pediatric patients: A systematic review

Contact Info

Product

Resources

About