Isolated choroidal metastasis from primary adenocarcinoma of the distal esophagus: a case report

Abstract

We present a case of a 41-year-old male patient who, 1 year after transhiatal esophagectomy and transmediastinal gastroplasty for an adenocarcinoma of the distal esophagus, presented with an isolated metastasis in the choroids of the left eye. Because of pains caused by secondary glaucoma, enucleation of the left eyeball had to be performed as the treatment of choice. At 1 year after surgery of the eye, the secondaries in both adrenal glands were revealed. Despite the applied chemotherapy, the patient died with signs of generalized disease 3 years after the initial surgery.

Bilateral Choroidal Metastases from Primary Esophageal Melanoma

“…Furthermore, in specific cases where cell types of the primary esophageal carcinoma were identified, all cases of choroidal metastases originated from adenocarcinoma. 4,16,17 To the best of the authors' knowledge, metastatic melanoma from primary esophageal melanoma has never been isolated in the choroid.…”

Choroidal metastasis from esophageal squamous cell carcinoma

“…The previous reports often mentioned the infrequency of EAC choroidal metastasis. [ 8 9 10 ] According to the literatures searched from MEDLINE and our case, 11 cases of EAC with choroidal metastasis were identified,[ 8 9 10 11 12 13 14 15 16 17 ] whereas four cases of choroidal tumor from ESCC were documented. [ 18 19 20 ]…”

Adenocarcinoma of the esophagus presenting as choroidal metastasis

“…Adenocarcinoma of the esophagus is an exceedingly rare cause of choroidal metastasis, with only six cases reported in the literature. [11][12][13][14][15] In recent years, there has been an increase in the incidence of adenocarcinoma of the distal esophagus. 16,17 Gastroenterologists and ophthalmologists need to be aware of the metastatic potential of these lesions to the eye, and a full ophthalmic examination can be an important part of the staging procedure.…”