Isolated plexiform neurofibroma mimicking a vascular lesion

Stefano, Paola Cecilia; Apa, Sebastián N; Lanöel, Agustina; María, Josefina Sala; Sierre, Sergio; Pierini, Adrián Martín

doi:10.1590/abd1806-4841.20164300

Cited by 9 publications

(14 citation statements)

References 5 publications

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“…They generally exhibit hypo- to isointense signal to muscle on T1-weighted images and hyperintense signal on T2-weighted sequences, with a variable enhancement pattern and foci of heterogenity. [15] Due to the small tumor size, peripheral location, and nonspecific imaging features of nail bed solitary neurofibroma MRI was rarely used for preoperative diagnosis. In only one case MRI was used and the exam characterized neurofibroma as a hyperintense mass on T2-weighted image.…”

Section: Discussionmentioning

confidence: 99%

Nail bed solitary neurofibroma

Perţea¹,

Grosu²,

Terinte

et al. 2019

Medicine

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Rationale:Nail bed solitary neurofibroma is an extremely rare tumor, with only 9 cases recorded in the literature so far.Patient concern:We present the case of a 42-year-old female patient, with a history of a slowly growing tumor in the nail bed of the left index and no clinical features of type I neurofibromatosis.Diagnosis:Nail bed solitary neurofibroma.Intervention:The tumor was surgically removed and the pathology examination established the diagnosis of neurofibroma.Outcomes:The postoperative outcome was good, with no recurrence 12 months after surgery.Lessons:We present the rarity of this type of tumor localized in the nail bed, taking into consideration the only 9 cases recorded in the literature. Nail bed solitary neurofibroma should be also included in the differential diagnosis of a nail bed tumor.

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Section: Discussionmentioning

confidence: 99%

Nail bed solitary neurofibroma

Perţea¹,

Grosu²,

Terinte

et al. 2019

Medicine

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“…They can be present at birth, but often appear between the ages of 2 and 5 [6]. It occurs frequently in the head and neck region due to the rich nerve innervations; however, it also appears on rare occasions in the extremities [7].…”

Section: Discussionmentioning

confidence: 99%

“…They entail pigmented, overlying skin with an angiomatous aspect; hypertrichosis may also be located in the lesion, producing a nevoid aspect, also seen in our patient. Two main features stand out: hyper extensibility with a lack of elasticity [6]. They arise as a diffuse mass from nerve trunk and lead to overgrowth of cutis and sub cutis structure and give a characteristic appearance of "Bag of worm" [9].…”

Section: Discussionmentioning

confidence: 99%

Giant Plexiform Neurofibroma of the Pelvic Region: Unusual Presentation in an Uncommon Location (About a Case)

Senhaji¹

2018

JDC

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Plexiform neurofibroma is a rare benign tumor of the peripheral tissue cells developed in the perineurium, generally associated with neurofibromatosis type 1 (NF1). These entities consist of multiple, twisted masses that grow along the axis of a large nerve, infiltrating and separating normal nerve fascicles. The diagnosis is essentially pathological and treatment is primarily surgical to avoid malignant degeneration. Giant neurofibromas are very difficult to manage surgically as they are extensively infiltrative and highly vascularized. This report describes a case of an advanced plexiform neurofibroma of the right lower back and pelvic region in a 25-year-old female with neurofibromatosis type 1, discovered in early childhood, with limited normal living due to the severe disfigurement as the result of progression of the disease.

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“…They have been found commonly over head and neck region though some unusual locations have also been reported [7][8][9].…”

Section: Case Reportmentioning

confidence: 99%