Isolated splenic hemangioma presenting with bleeding into serous body cavities

Meera, A. V.; Sen, Sudipta; Raghupathy, P.; Walter, David F.; Chandy, Mathew J.; Krishnaswami, H; Chacko, Jacob; Zachariah, Ninan; Mammen, K. E.

doi:10.1007/bf00182234

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“…Generalized splenomegaly may be present, but blood tests are often normal. Splenic hemangioma may occur as part of generalized angiomatosis, as seen in Klippel-Trenaunay syndrome or Kasabach-Meritt syndrome [ 6 , 7 ]. There was no clinical or laboratory evidence associating either syndrome to our case.…”

Section: Discussionmentioning

confidence: 99%

“…Splenectomy may be efficacious in the correction of coagulation abnormalities in Kassabach-Meritt syndrome associated with ruptured giant splenic hemangiomas [ 6 , 7 ]. An alternative approach is partial splenectomy, especially in childhood when the preservation of the spleen as an essential part of the developing immune system appears to be of vital importance.…”

Section: Discussionmentioning

confidence: 99%

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Co-existence of a giant splenic hemangioma and multiple hepatic hemangiomas and the potential association with the use of oral contraceptives: a case report

et al. 2008

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IntroductionHepatic and splenic hemangiomas are common benign tumors that mainly affect female patients. Giant splenic hemangiomas are extremely rare, especially when correlated with multiple hepatic hemangiomas. Pathogenetic mechanisms between hemangiomas and oral contraceptives, as well as therapeutic approaches, are analyzed in this case report, in particular for the management of synchronous splenic and hepatic hemangiomas.Case presentationWe report here a 42-year-old woman with a giant splenic hemangioma, multiple hepatic hemangiomas and a history of oral estrogen intake for many years. At first it was difficult to determine the organ from which the giant hemangioma originated. Angiography proved extremely helpful in tracing its origin in the spleen. Hematomas in the giant hemangioma posed a significant threat of rupture and catastrophic hemorrhage. We left the small hepatic hemangiomas in place, and removed the spleen along with the giant splenic hemangioma.ConclusionDiagnostic pitfalls in the determination of the origin of this giant hemangioma, attribution of its origin to the spleen angiographically, the unusual co-existence of the giant splenic hemangioma with multiple hepatic ones, and the potential threat of rupture of the giant hemangioma are some of the highlights of this case report. Estrogen administration represents a pathogenic factor that has been associated with hemangiomas in solid organs of the abdominal cavity. The therapeutic dilemma between resection and embolization of giant hemangiomas is another point of discussion in this case report. Splenectomy for the giant splenic hemangioma eliminates the risk of rupture and malignant degeneration, whereas observation for the small hepatic ones (<4 cm) was the preferable therapeutic strategy in our patient.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%