Isolation and antifungal activity evaluation of Satureja khuzestanica Jamzad extract against some clinically important dermatophytes

Sadeghi-Nejad, Batool; Rezaei‐Matehkolaei, Ali; Naanaie, Sedigheh Yusef

doi:10.1016/j.mycmed.2017.08.002

Cited by 8 publications

(3 citation statements)

References 18 publications

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“…The MICs obtained in this study compared with the results of previous studies are provided in Table 2. Previously reported MIC 50 ranges for T. mentagrophytes-interdigitale of various antifungal drugs were similar to those observed in the present study (8,(19)(20)(21)(22). The MIC distributions of itraconazole, miconazole, luliconazole, voriconazole, ketoconazole, sertaconazole, naftifine, ciclopirox olamine, and clotrimazole show good susceptibility of T. mentagrophytes-interdigitale complex compared to terbinafine, fluconazole, and griseofulvin.…”

Section: Discussionsupporting

confidence: 90%

MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin

Shaw

Singh

Dogra

et al. 2020

Antimicrob Agents Chemother

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Dermatophytosis due to the Trichophyton mentagrophytes-Trichophyton interdigitale complex is being increasingly reported across India. Reports of therapeutic failure have surfaced recently, but there are no clinical break points (CBP) or epidemiological cutoffs (ECVs) available to guide the treatment of dermatophytosis. In this study, a total of 498 isolates of the T. mentagrophytes-interdigitale complex were collected from six medical centers over a period of five years (2014 to 2018). Antifungal susceptibility testing of the isolates was carried out for itraconazole, fluconazole, ketoconazole, voriconazole, luliconazole, sertaconazole, miconazole, clotrimazole, terbinafine, amorolfine, naftifine, ciclopirox olamine, and griseofulvin. The MICs (in mg/liter) comprising >95% of the modeled populations were as follows: 0.06 for miconazole, luliconazole, and amorolfine; 0.25 for voriconazole; 0.5 for itraconazole, ketoconazole, and ciclopirox olamine; 1 for clotrimazole and sertaconazole; 8 for terbinafine; 16 for naftifine; 32 for fluconazole; and 64 for griseofulvin. A high percentage of isolates above the upper limit of the wild-type MIC (UL-WT) were observed for miconazole (29%), luliconazole (13.9%), terbinafine (11.4%), naftifine (5.2%), and voriconazole (4.8%), while they were low for itraconazole (0.2%). Since the MICs of itraconazole were low against the T. mentagrophytes-interdigitale complex, this could be considered the choice of first-line treatment. The F397L mutation in the squalene epoxidase (SE) gene was observed in 77.1% of isolates with a terbinafine MIC of ≥1 mg/liter, but no mutation was detected in isolates with a terbinafine MIC of <1 mg/liter. In the absence of CBPs, evaluation of the UL-WT may be beneficial for managing dermatophytosis and monitoring the emergence of isolates with reduced susceptibility.

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Section: Discussionsupporting

confidence: 90%

MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin

Shaw

Singh

Dogra

et al. 2020

Antimicrob Agents Chemother

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“…Determination of MIC and MFC values of the most potential extract of M. speciosa Blume fruit against C. albicans ATCC 10231 and/or T. rubrum ATCC 28188 were performed in 96well microtiter plates, using two-fold broth microdilution methods in triplicates [16,17] with some modifications according to procedures of Nejad [18]. The crude extract of M. speciosa Blume was dissolved in 2% v/v DMSO, at a concentration of 10 % w/v or 100,000 ppm served as a stock solution.…”

Section: Concentration (Mic) and Minimum Fungicidal Concentration (Mfc) Valuesmentioning

confidence: 99%

“…Another important phytochemical compound in ethyl acetate extract to triterpenes is also reported to possess numerous antimicrobial activities [27]. Natural triterpenoids are present in herbal medicines and some of them give evidence concerning the antifungal activity of natural sources [18,27]. Several publications have documented the antifungal activities of essential oil and plant extracts [28,29].…”

Section: Antifungal Activity Testmentioning

confidence: 99%

Antifungal activities of Medinilla speciosa Blume fruit extracts against Candida albicans and Trichophyton rubrum

Milanda¹,

Fitri²,

Barliana³

et al. 2021

J Adv Pharm Educ Res

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Antifungal activity of aminoalcohols and diamines against dermatophytes and yeast

et al. 2020

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Isolation and antifungal activity evaluation of Satureja khuzestanica Jamzad extract against some clinically important dermatophytes

Cited by 8 publications

References 18 publications

MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin

MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin

Antifungal activities of Medinilla speciosa Blume fruit extracts against Candida albicans and Trichophyton rubrum

Antifungal activity of aminoalcohols and diamines against dermatophytes and yeast

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