Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation

Çakır, Ahmet; Mavi, Ahmet; Yıldırım, Ali Osman; Duru, Mehmet Emin; Harmandar, Mansur; Kazaz, Cavit

doi:10.1016/s0378-8741(03)00112-0

Cited by 170 publications

(119 citation statements)

References 47 publications

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“…Antioxidant activities of the acetone, ethanol, and water extracts of 20 plant species were determined using the thiocyanate method (Cakir et al, 2003(Cakir et al, , 2006. Briefly, extract solutions (30 µg/mL) were mixed with 2.5 mL 0.02 M linoleic acid (Fluka emulsion containing equal weight of Tween-20 in pH 7.4 phosphate-buffered saline; Sigma), and the final volume was adjusted to 5 mL with phosphatebuffered saline (pH 7.4) in a test tube and incubated in darkness at 40…”

Section: Antioxidant Activitymentioning

confidence: 99%

“…However, these natural antioxidant mechanisms can be inefficient, and hence dietary intake of antioxidant compounds becomes important (Espin et al, 2000). Natural antioxidants constitute broad ranges of compounds including phenolics, carotenoids, α-tocopherols, and vitamin C (Velioglu et al, 1998;Cakir et al, 2003Cakir et al, , 2006. Medicinal plants and herbs are diverse sources of natural antioxidants.…”

Section: Introductionmentioning

confidence: 99%

“…Medicinal plants and herbs are diverse sources of natural antioxidants. Therefore, there is a great interest concerning the antioxidant properties of medicinal plants and herbs (Velioglu et al, 1998;Cakir et al, 2003Cakir et al, , 2006Ismaili et al, 2004;Sokmen et al, 2004;Salehi et al, 2005;Erdemoglu et al, 2006;Ozgen et al, 2006). This study was undertaken to determine the potential antimicrobial, antioxidant, and free radical scavenging activities of the extracts of some Turkish native herbs.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

Unal

Mavi

Kara

et al. 2008

Pharmaceutical Biology

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The antimicrobial activities of chloroform, acetone, ethanol, and water extracts of 25 plants, mostly used as remedies against various diseases in Turkish traditional medicine, were tested against 10 pathogenic bacteria and one fungus (Candida albicans) using the disk diffusion method. Among the tested plant species, Ziziphora clinopodioides Lam (Labiatae), Thymus fallax Fisch et Mey. (Labiatae), and three Hypericum species [H. heterophyllum Vent., H. hyssopifolium Chaix. subsp. elongatum (Ledeb.) Woron var. elongatum, and H. scabrum L.] (Guttiferae) showed antimicrobial activity at a broader spectrum. In particular, chloroform, acetone, and ethanol extracts of Z. clinopodioides inhibited the growth of all microbial species. Minimal inhibition concentration values of Z. clinopodioides extracts were also found to be low. The antioxidant activity of the acetone, ethanol, and water extracts of 20 plants was also evaluated by lipid peroxidation inhibition and DPPH free radical scavenging methods. It was found that water, ethanol, and acetone extracts of Z. clinopodioides, T. fallax, three Hypericum species, Artemisia santonicum L. (Compositae), and Echinophora tenuifolia L. subsp. sibthorpiena (Umbelliferae) have strong antioxidant activities among the tested plant species. In general, there is a correlation between the antioxidant potential and total phenolic contents of the extracts. In light of the current study, it can be concluded that Z. clinopodioides and T. fallax may have potential use in the food industry as antioxidants and antimicrobial herbs, as well as pharmaceutical interest.

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Section: Antioxidant Activitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

Unal

Mavi

Kara

et al. 2008

Pharmaceutical Biology

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“…Çalışmamızda kullandığımız kantaron ektresinin içerdiği flavanoid ve fenolik bileşiklerden dolayı potansiyel antioksadatif özelliği vardır (20)(21). Kantaron ekstresinin çalışmamızda gösterdiğimiz gentamisinin neden olduğu ototoksisite üzerinde koruyucu etkisi bu özelliğinden kaynaklanmış olabilir.…”

Section: Discussionunclassified

Kantaron Ekstresinin Gentamisinin Neden Oldugu Ototoksisite Uzerinde Koruyucu Etkisi

2017

GMJ

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“…Due to differences in calculation procedures (μmol α-tocopherol/g of extract) to make comparison with the current study had not been possible. Based on the results of various studies [30,31] it can be said that phenolic substances in the context of a plant extract and synergistic interactions may be responsible for its antioxidant activity [2].…”

Section: Antioxidant Activitiesmentioning

confidence: 99%

Antioxidant activity of Trachystemon orientalis (L.) G. Don (Borage) grown and eaten as food in Ordu, Turkey

Ayvaz

2015

Herba Polonica

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SummaryIntroductıon: Instead of synthetic antioxidants, using of natural products with antioxidant activity is demanded.Objectıve: The aim of this study is to evaluate the antioxidant activity and total phenolic and flavonoid contents of theTrachystemon orientalis(borage) obtained from Ordu.Methods: The water and ethanol extracts of the borage plant were investigated by using severalin vitroantioxidant activity tests such as total antioxidant capacity, O2•−,•OH, DPPH and ABTS radicals scavenging activities, hydrogen peroxide scavenging activity, FRAP, Fe2+chelating and reducing power assays in order to make effective comparisons.Results: Water extract of theT. orientalishad the more phenolic (90 mg GA/g extract) and flavonoid (56.88 mg CT/g extract) contents than ethanol extract. Furthermore, both of the extracts showed strong antioxidant and radical scavenging activities determined by differentin vitromodels. The highest total antioxidant capacity as ascorbic acid equivalents of 244.50 mg/g extract was also calculated for water extract. Generally, a relationship between total phenolic content and antioxidant activity was established. It is also an important finding for an edible food source that the phenolic and flavonoid content and antioxidative activities for water extract was higher than the ethanol extract.Conclusıon:T. orientaliscould be used as a food ingredient instead of synthetic antioxidants and all results will contribute to the recent increase in investigations on using natural products in many areas such as food, pharmacy, alternative medicine and natural therapy.

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Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation

Cited by 170 publications

References 47 publications

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

Kantaron Ekstresinin Gentamisinin Neden Oldugu Ototoksisite Uzerinde Koruyucu Etkisi

Antioxidant activity of Trachystemon orientalis (L.) G. Don (Borage) grown and eaten as food in Ordu, Turkey

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