Isolation, characterization and hypolipidemic activity of ferulic acid in high-fat-diet-induced hyperlipidemia in laboratory rats

Tibet Kefir Milk Regulated Metabolic Changes Induced by High-Fat Diet via Amino Acids, Bile Acids, and Equol Metabolism in Human-Microbiota-Associated Rats

“…28,29 An increase in serum TG increases the risk of cardiovascular disease. 30 A significant decrease in serum TG was observed after TKM intervention for 8 weeks, which shows that TKM helps reduce serum TG and thus has a positive effect on health.…”

“…Abdominal obesity is a major cause of dyslipidemia which is characterized by elevated serum TG, LDL, and TC levels; whereas TG are the main constituents of body fat. HFD-fed mice showed a higher level of visceral fat accumulation, which shows that they probably failed to adequately store excessive TG which caused elevation in serum TG levels. , An increase in serum TG increases the risk of cardiovascular disease . A significant decrease in serum TG was observed after TKM intervention for 8 weeks, which shows that TKM helps reduce serum TG and thus has a positive effect on health.…”

In Situ Cross-Linkable Hyaluronic–Ferulic Acid Conjugate Containing Bucladesine Nanoparticles Promotes Neural Regeneration after Spinal Cord Injury

“…The chemical structure of the HASH-FA conjugate was further confirmed by 1 H NMR analysis (Figure C). FA demonstrated signals at 3.85 ppm (OCH 3 ), 6.33–6.36 ppm (H h ), 6.77–6.78 ppm (H e ), 7.08–7.11 ppm (H f ), 7.26 ppm (H b ), 7.46–7.49 ppm (H g ), 9.52 ppm (phenolic OH), and a very weak peak at 12.10 ppm related to the proton of carboxylic acid group . HA showed a broad signal between 3.32 and 3.79 ppm related to the protons in the sugar ring, a characteristic peak at about 4.79 ppm attributed to the anomeric protons, and a signal at 1.98 ppm related to the protons of methyl N -acetyl group .…”

“…FA demonstrated signals at 3.85 ppm (OCH 3 ), 6.33−6.36 ppm (H h ), 6.77−6.78 ppm (H e ), 7.08−7.11 ppm (H f ), 7.26 ppm (H b ), 7.46−7.49 ppm (H g ), 9.52 ppm (phenolic OH), and a very weak peak at 12.10 ppm related to the proton of carboxylic acid group. 35 HA showed a broad signal between 3.32 and 3.79 ppm related to the protons in the sugar ring, a characteristic peak at about 4.79 ppm attributed to the anomeric protons, and a signal at 1.98 ppm related to the protons of methyl N-acetyl group. 36 Besides the distinct peaks of the HA backbone in the upfield region, the characteristic signals of FA in the downfield region were well observed in HASH-FA.…”

A possible new activator of PI3K‐Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction

“… 34 Paeoniflorin can also regulate hepatic cholesterol synthesis and metabolism, as well as improve blood lipid levels. 35 Ferulic acid similarly improves blood lipid 36 metabolism and can attenuate apoptosis caused by AMI by enhancing autophagy. 37 Astragalosides can recover impaired ventricular function and prevent cardiac remodelling induced by hypercholesterolemia via antioxidative stress and regulation of cardiac homeostasis.…”