Isolation, structure, and surfactant properties of polysaccharides from Ulva lactuca L. from South China Sea

Tian, Hua; Yin, Xijie; Zeng, Qinghuan; Zhu, Liang; Chen, Junhua

doi:10.1016/j.ijbiomac.2015.05.031

Cited by 77 publications

(53 citation statements)

References 36 publications

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“…Ulva lactuca L. is a common green macroalga in the division Chlorophyta and found widespread in China (Tian, Yin, Zeng, Zhu, & Chen, 2015). Polysaccharides isolated from U.…”

Section: Chlorophyta (Green Algae)mentioning

confidence: 99%

Bioactive compounds from marine macroalgae and their hypoglycemic benefits

Zhao

Yang

Liu

et al. 2018

Trends in Food Science & Technology

207

102

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Bioactive compounds from marine macroalgae and their hypoglycemic benefits http://researchonline.ljmu.ac.uk/id/eprint/7721/ Article LJMU has developed LJMU Research Online for users to access the research output of the University more effectively.Abstract: Diabetes mellitus is a group of chronic metabolic disorders characterized by hyperglycemia due to defects in insulin action and/or secretion. It is a worldwide problem which has led to illness and premature mortality for many people, and the number of diabetes cases has been rising sharply. Unluckily, many conventional antidiabetic agents either show limited efficacy or serious mechanism-based side effects. Marine macroalgae possess tremendous nutritional value and have been well-known to cure and prevent diabetes. An increased interest in various bioactive natural products from marine macroalgae, as a potential source of effective antidiabetic agents, has been observed in recent years. The effects of macroalgae may delay the development of diabetes and alter the metabolic abnormalities through various mechanisms of actions. This review provides an overview of marine macroalgae used to prevent and manage diabetes and explores the hypoglycemic properties of macroalgae-derived bioactive compounds such as polyphenol, bromophenols, sulfated polysaccharides, fucoidan, fucosterol, phlorotannins, carotenoid pigments and fucoxanthin with their probable mechanisms behind hypoglycemic activity. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent α-glucosidase and α-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice.

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“…Ulva lactuca L. is a common green macroalga in the division Chlorophyta and found widespread in China (Tian, Yin, Zeng, Zhu, & Chen, 2015). Polysaccharides isolated from U.…”

Section: Chlorophyta (Green Algae)mentioning

confidence: 99%

Bioactive compounds from marine macroalgae and their hypoglycemic benefits

Zhao

Yang

Liu

et al. 2018

Trends in Food Science & Technology

207

102

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“…23 The wavenumbers between 800 and 1200 cm −1 represent the finger print region for carbohydrates. 27,29,30 And the signals from other monosaccharides cannot be detected, which maybe due to their much lower content when compared to xylose. 25 Furthermore, the band appearing at 896 cm −1 is typical of β-xylans, and it is ascribed to glycosidic C 1 -H deformation mode with ring vibration contribution and OH bending modes.…”

Section: Preparation and Structural Characterization Of Nvpsmentioning

confidence: 99%

Isolation and antitumor efficacy evaluation of a polysaccharide from Nostoc commune Vauch.

et al. 2015

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Nostoc commune Vauch. has been traditionally used as a healthy food and medicine for centuries especially in China. It has been demonstrated that the polysaccharides isolated from Nostoc commune Vauch. exhibit strong antimicrobial and antioxidant activities. However, little is known about their anticancer activities and the underlying mechanisms of action. Herein, we report the isolation of a polysaccharide from Nostoc commune Vauch. (NVPS), and its physicochemical properties were analyzed. In an attempt to demonstrate the potential application of NVPS in tumor chemotherapy, the in vitro antitumor activity was determined. NVPS significantly suppressed the growth and proliferation of MCF-7 and DLD1 cells. The molecular mechanism underlying this in vitro antitumor efficacy was elucidated, and the results indicated that NVPS simultaneously triggered intrinsic, extrinsic and endoplasmic reticulum stress (ERS)-mediated apoptotic signaling pathways. Collectively, these findings demonstrate that NVPS could be used as a novel promising source of natural antitumor agents.

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“…Previous studies have shown that ULP had potent effects on cholesterol lowering, immunomodulatory and anti-heptotoxic property in vivo and in vitro [17, 18]. ULP consisting of rhamnose, xylose, glucose, uronic acid, and sulfate was shown to stabilize the functional status of bio-membranes and act as an antioxidant and surfactant [18–20]. Accordingly, we set out to design SeNPs decorated with ULP and hypothesized that these SeNPs would exhibit anti-inflammatory activity accompanied by low toxicity for functionally attenuating IBD.…”

Section: Introductionmentioning

confidence: 99%

Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-κB mediated hyper inflammation

et al. 2017

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BackgroundSelenium (Se) is an essential micronutrient trace element and an established nutritional antioxidant. Low Se status exacerbates inflammatory bowel diseases progression, which involves hyper inflammation in the digestive tract. Se nanoparticles (SeNPs) exhibit anti-inflammatory activity accompanied by low toxicity, especially when decorated with natural biological compounds. Herein, we explored the beneficial effects of SeNPs decorated with Ulva lactuca polysaccharide (ULP) in mice subjected to the acute colitis model.ResultsWe constructed SeNPs coated with ULP (ULP-SeNPs) in average diameter ~130 nm and demonstrated their stability and homogeneity. Supplementation with ULP-SeNPs (0.8 ppm Se) resulted in a significant protective effect on DSS-induced acute colitis in mice including mitigation of body weight loss, and colonic inflammatory damage. ULP-SeNPs ameliorated macrophage infiltration as evidenced by decreased CD68 levels in colon tissue sections. The anti-inflammatory effects of ULP-SeNPs were found to involve modulation of cytokines including IL-6 and TNF-α. Mechanistically, ULP-SeNPs inhibited the activation of macrophages by suppressing the nuclear translocation of NF-κB, which drives the transcription of these pro-inflammatory cytokines.ConclusionsULP-SeNPs supplementation may offer therapeutic potential for reducing the symptoms of acute colitis through its anti-inflammatory actions.Electronic supplementary materialThe online version of this article (doi:10.1186/s12951-017-0252-y) contains supplementary material, which is available to authorized users.

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Isolation, structure, and surfactant properties of polysaccharides from Ulva lactuca L. from South China Sea

Cited by 77 publications

References 36 publications

Bioactive compounds from marine macroalgae and their hypoglycemic benefits

Bioactive compounds from marine macroalgae and their hypoglycemic benefits

Isolation and antitumor efficacy evaluation of a polysaccharide from Nostoc commune Vauch.

Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-κB mediated hyper inflammation

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