Isolation, structure, biological activity and application progress of ginseng polysaccharides from the Araliaceae family

Liu, Silu; Geng, Jianan; Chen, Weijia; Zong, Ying; Zhao, Yan; Du, Rui; He, Zhongmei

doi:10.1016/j.ijbiomac.2024.133925

International Journal of Biological Macromolecules

2024

DOI: 10.1016/j.ijbiomac.2024.133925

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Isolation, structure, biological activity and application progress of ginseng polysaccharides from the Araliaceae family

Silu Liu,

Jianan Geng,

Weijia Chen

et al.

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Cited by 2 publications

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Review: Gut microbiota: Therapeutic targets of ginseng polysaccharides against multiple disorders

Wang,

Xin

2025

International Journal of Biological Macromolecules

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Review: Gut microbiota: Therapeutic targets of ginseng polysaccharides against multiple disorders

Wang,

Xin

2025

International Journal of Biological Macromolecules

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A Comparative Study of the Chemical Composition and Skincare Activities of Red and Yellow Ginseng Berries

Wang,

Han,

et al. 2024

Molecules

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This study was conducted to investigate the differences in chemical composition between red (RGBs) and yellow ginseng berries (YGBs) and their whitening and anti-aging skincare effects. The differences in the chemical composition between RGB and YGB were analyzed by ultra-high-performance liquid chromatography tandem quadrupole electrostatic field orbit trap mass spectrometry (UHPLC-Q-Exactive-MS/MS) combined with multivariate statistics. An aging model was established using UVB radiation induction, and the whitening and anti-aging effects of the two ginseng berries were verified in vitro and in vivo using cell biology (HaCaT and B16-F10 cells) and zebrafish model organisms. A total of 31 differential compounds, including saponins, flavonoids, phenolic acids, and other chemical constituents, were identified between the two groups. Superoxide dismutase (SOD) activity was more significantly increased (p < 0.05) and malondialdehyde (MDA) content was more significantly decreased (p < 0.01) in RGB more than YGB induced by UVB ultraviolet radiation. In terms of whitening effects, YGB was more effective in inhibiting the melanin content of B16-F10 cells (p < 0.01). The results of zebrafish experiments were consistent with those of in vitro experiments and cell biology experiments. The DCFH fluorescence staining results revealed that both ginseng berries were able to significantly reduce the level of reactive oxygen species (ROS) in zebrafish (p < 0.01). Comparison of chemical composition and skin care activities based on RGB and YGB can provide a theoretical basis for the deep development and utilization of ginseng berry resources.

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Isolation, structure, biological activity and application progress of ginseng polysaccharides from the Araliaceae family

Cited by 2 publications

References 103 publications

Review: Gut microbiota: Therapeutic targets of ginseng polysaccharides against multiple disorders

Review: Gut microbiota: Therapeutic targets of ginseng polysaccharides against multiple disorders

A Comparative Study of the Chemical Composition and Skincare Activities of Red and Yellow Ginseng Berries

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