Isolierte unklare Trommelfellbefunde

Gurr, A.; Ebsen, Michael; Stark, Th.

doi:10.1007/s001060170083

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Table 2 summarizes the data found in the English literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] .…”

Section: Discussionmentioning

confidence: 99%

“…RCT: randomized controlled trial • a white mass inserted into a normal pars tensa, without connection with the pars flaccida and/or promontorium; • normal pars flaccida; • no prior history of otorrhea or TM perforation; • no previous otologic procedures or trauma. Five studies [6,7,11,13,20] described a total of 14 cases of 36 pediatric patients with a history of recurrent otitis media; however, they were classified as "congenital" because they did not show anamnestic records of otorrhea, TM perforation, previous otologic procedures, or ear trauma. In all the living adult case's ITMCs, we did not find any otologic history (or previous otitis media episodes) and no inflammatory processes were found intraoperatively.…”

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Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Pedruzzi

Mion²,

Comacchio³

2016

Int Adv Otol

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Congenital cholesteatoma within the tympanic membrane is an uncommon entity, with only few cases being documented. The aetiopathogenesis of this lesion is still unknown; however, when cholesteatoma develops in subjects without any history of previous ear inflammation, as in the case we report here, an embryologic origin is deeply suspected. An acquired origin is hypothesized in patients with a previous history of an inflammatory process of the external or middle ear because of the proliferation of the basal cell layer of the tympanic membrane epithelium. We report a rare case of congenital cholesteatoma of the tympanic membrane in an adult patient and review the literature KEYWORDS: Congenital intratympanic cholesteatoma, intratympanic cholesteatoma, congenital cholesteatoma of the tympanic membrane, cholesteatoma of the tympanic membrane Barbara Pedruzzi, Marta Mion, Francesco ComacchioDepartment of Otolaryngology, Azienda Ospedaliera di Padova, Padova, Italy Case ReportIn 1936, Teed [3] cited the first five cases of ITMC to support the theory of a congenital origin of cholesteatomas. From the English literature, he cited the first case reported by Hinton in 1863 [4] and one other case.We identified a list of potential citations for inclusion in this review, following which the titles and abstracts on this list were screened by two independent reviewers.All the retrieved full-texts were included in the review by consensus of all the authors ( Figure 5).As a quality assessment strategy, the included studies were methodologically appraised according to the National Institute for Health and Clinical Excellence's levels of evidence (Table 1): all the studies could be categorized as evidence level 3.We analyzed the data from these cases, including our own case, to study their demographic details, and clinical features and management, for a total of 42 patients and 20 articles, including our own research (Table 2). Table 2 summarizes the data found in the English literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] . 120J Int Adv Otol 2016; 12(1): 119-24 The age range was 5 months to 57 years, with 27 (64.3%) cases involving patients less than 4 years of age, out of which seven (16.7%) were 1-year old or less. There was a history of one or more episodes of otitis media (n=14) when ITMC was noticed on otoscopy. The lesion was first noted by pediatricians (n=14), by general practitioners (n=4), or by otolaryngologists (n=16). In three cases, the analyses were conducted post-mortem during autoptic exams [9] . This highlights the need for routine otoscopy by primary care physicians to detect abnormalities and make an early referral to otolaryngologists. ITMC should always be considered in the differential diagnosis of white lesions in TM. Otomicroscopy can help differentiate ITMC from tympanosclerosis. Only in one case had the lesion occupied the whole TM, while the umbo was involved in nine patients; this region is the most depressed part of TM, where the manubrium of the malleus is fir...

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“…Table 2 summarizes the data found in the English literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] .…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Pedruzzi

Mion²,

Comacchio³

2016

Int Adv Otol

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Principles of cholesteatoma surgery

Stark

Gurr

Sudhoff

2011

HNO

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As a potentially life-threatening disease, cholesteatoma of the petrous bone generally requires a surgical approach. Surgery aims to produce an ear that is easy to care for and is free of recurrent or residual cholesteatoma. Hearing improvement is of secondary importance. Nevertheless the sound conduction system is generally reconstructed as a single-stage procedure. There are various possible methods of dealing with a cholesteatoma: (i) preserving or reconstructing the posterior meatal wall with an aerated mastoid (closed technique) or obliteration of the mastoid completely or partially after removal of the posterior wall (closed technique); and (ii) leaving the cavity open for inspection (open technique). In our opinion any technique where the mastoid is not open for inspection should be called a closed technique. Both techniques have their specific advantages and disadvantages.

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Dark energy: recent observations and future prospects

Perlmutter

2003

Philosophical Transactions of the Royal Society of London. Seri

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Dark energy presents us with a challenging puzzle: understanding the new physics seen in the acceleration of the expansion of the Universe. Measurements using type-Ia supernovae (SNe) first detected this acceleration, and this approach remains the most direct route to studying the details of the Universe's expansion history that can teach us more about the nature of the dark energy. Such measurements are, however, extremely demanding in both precision and accuracy, since the different dark-energy models predict very small differences in the expansion history. While several cosmological probes may reach the required statistical uncertainties, the key measurement limit will be the systematic uncertainty. The supernova-measurement approach has the advantage of well-studied systematic uncertainties, allowing a next-generation experiment to be pursued. We briefly review the progress to date and examine the promise of future surveys with large numbers of SNe and well-bounded systematics.

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Isolierte unklare Trommelfellbefunde

Cited by 3 publications

References 4 publications

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature

Principles of cholesteatoma surgery

Dark energy: recent observations and future prospects

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