2024
DOI: 10.1001/jamaneurol.2024.2213
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Itching Frequency and Neuroanatomic Correlates in Frontotemporal Lobar Degeneration

Rafi Hadad,
Maria Luisa Mandelli,
Katherine P. Rankin
et al.

Abstract: ImportanceItching is common in geriatric populations and is frequently linked to dermatological or systemic conditions. Itching engages specific brain regions that are implicated in the pathogenesis of frontotemporal lobar degeneration spectrum disorders (FTLD-SD). Thus, itching of undetermined origin (IUO) may indicate the presence of a neurodegenerative process.ObjectiveTo compare the frequency of itching in FTLD-SD and Alzheimer disease (AD) and to determine the neuroanatomical underpinnings of IUO.Design, … Show more

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