“…4,26 Cholinergic urticaria, commonly reported in runners, is characterized by 2-to 4-mm, well-defined, erythematous, pruritic wheals that develop within 2 to 30 minutes after a general overheating of the body from environmental temperature, exertion, exercise, or stress. 4,20,26,39,40 This type of urticaria has a predilection for the upper thorax and neck, but may spread to the rest of the body. 40 Systemic symptoms may include abdominal cramps, diarrhea, nausea, vomiting, salivation, headache, syncope, and hypotension.…”