IVF twins: buy one get one free?

Ismail, L.; Mittal, Monica; Kalu, Emmanuel

doi:10.1136/jfprhc-2011-100263

Cited by 9 publications

(9 citation statements)

References 40 publications

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“…Patients may not be willing to risk a failed cycle given the financial, emotional, and physical burden associated with IVF. Furthermore, many patients desire twins and do not fully consider the risks associated with twin pregnancies and births [28, 29]. However, providing patients with personalized counseling, access to educational information regarding the risks of DET and multiple births, financial incentives, tools to help predict the chances of IVF success, and technologies to select high-quality embryos for transfer should help to increase the use of eSET in clinical practice.…”

Section: Discussionmentioning

confidence: 99%

“…Multiple factors impact patients’ embryo transfer decision, including nulliparity, family income, level of knowledge regarding the risks of multiples, patient age, duration of infertility, and the desire to limit the physical and psychological stress of multiple IVF cycles [27–29]. …”

Section: Introductionmentioning

confidence: 99%

“…Many patients express a preference for siblings, or even twins, and thus may be more willing to accept the risks associated with multiple pregnancy [28, 29]. A survey of 449 infertile women found that one in five listed multiple birth as their most desired outcome [28].…”

Section: Introductionmentioning

confidence: 99%

“…All scenarios described a twin pregnancy rate of 25 % after DET versus 1 % after eSET. Additionally, patients who desire more than one child may want to attempt to complete their family in as few cycles as possible to avoid the emotional and psychological stress of further treatment [29].

Fig.…”

Section: Introductionmentioning

confidence: 99%

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Promoting the use of elective single embryo transfer in clinical practice

Tobias

Sharara

Franasiak

et al. 2016

Fertil Res and Pract

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BackgroundThe transfer of multiple embryos after in vitro fertilization (IVF) increases the risk of twins and higher-order births. Multiple births are associated with significant health risks and maternal and neonatal complications, as well as physical, emotional, and financial stresses that can strain families and increase the incidence of depression and anxiety disorders in parents. Elective single embryo transfer (eSET) is among the most effective methods to reduce the risk of multiple births with IVF.Main bodyCurrent societal guidelines recommend eSET for patients <35 years of age with a good prognosis, yet even this approach is not widely applied. Many patients and clinicians have been reluctant to adopt eSET due to studies reporting higher live birth rates with the transfer of two or more embryos rather than eSET. Additional barriers to eSET include risk of treatment dropout after embryo transfer failure, patient preference for twins, a lack of knowledge about the risks and complications associated with multiple births, and the high costs of multiple IVF cycles. This review provides a comprehensive summary of strategies to increase the rate of eSET, including personalized counseling, access to educational information regarding the risks of multiple pregnancies and births, financial incentives, and tools to help predict the chances of IVF success. The use of comprehensive chromosomal screening to improve embryo selection has been shown to improve eSET outcomes and may increase acceptance of eSET.ConclusionseSET is an effective method for reducing multiple pregnancies resulting from IVF. Although several factors may impede the adoption of eSET, there are a number of strategies and tools that may encourage the more widespread adoption of eSET in clinical practice.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fig.…”

Section: Introductionmentioning

confidence: 99%

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Promoting the use of elective single embryo transfer in clinical practice

Tobias

Sharara

Franasiak

et al. 2016

Fertil Res and Pract

View full text Add to dashboard Cite

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“…Lastly, SSM couples are not immune to the well-documented emotional, financial and time-related costs of ART and they may bear an additional burden of guilt for subjecting third-parties to such risk [28]. For these couples, success of treatment is reliant on the continued co-operation of third-parties and the availability of funding which cannot be guaranteed through multiple ART cycles that may be required.…”

Section: B) Issues For the Commissioning Couplementioning

confidence: 99%

The ethics of fertility treatment for same-sex male couples: Considerations for a modern fertility clinic

Mackenzie

Wickins-Drazilova

Wickins

2020

European Journal of Obstetrics & Gynecology and Reproductiv

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Social and legal equality for same-sex male couples continues to grow in many countries. Consequently, increasing numbers of same-sex male couples are seeking assisted reproductive technology to achieve parenthood. Fertility treatment for same-sex male couples is an undoubtedly complex issue and raises a variety of ethical concerns. Relevant considerations include ethical issues relating to the surrogate and a possible egg donor, the commissioning same-sex couple, the welfare of the child and the fertility clinic itself. This work analyses these arguments in the context of modern fertility services, providing reflection on the evidence present and what it means for clinicians today. Herein, we argue that fertility treatment for same-sex male couples via surrogacy agreements are acceptable, subject to considerations of each individual case, as in all assisted reproductive treatment. It is in the interest of open and equal access to health services that barriers to assisted reproductive technology for same-sex male couples should be minimised where possible.

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Mirror, mirror? An evaluation of identical twin mirroring in tooth crown morphology

McCrary,

Hughes,

Brook

et al. 2024

The Anatomical Record

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It has been estimated that 25% of monozygotic (“identical”) twin pairs exhibit reverse asymmetry (RA) or “mirroring” of minor anatomical features as a result of delayed zygote division. Here, we examine whether identical twin mirroring accounts for patterns of dental asymmetry in a sample of monozygotic and dizygotic (“fraternal”) twins. We focus on crown morphology to approach the following question: is there an association between dental RA frequency and twin type suggestive of the presence of mirror image twins in our sample? Data were collected from 208 deciduous and 196 permanent dentitions of participants of the University of Adelaide Twin Study using Arizona State University Dental Anthropology System standards. RA frequencies were compared across morphological complexes (deciduous, permanent), twin types (monozygotic, dizygotic), and traits. Fisher's exact tests were performed to formally evaluate the association between twin type and dental RA. Across the entire dataset, RA rates failed to exceed 8% for any twin type. In monozygotic twins, deciduous mirroring totaled 5.3% of observed cases, while permanent mirroring totaled 7.8% of observed cases. We found no statistically significant association between RA and twin type for any morphological character (p‐value range: 0.07–1.00). Our results suggest the timing of monozygotic twin division does not explain the structure of asymmetry for our morphology dataset and that published estimates of identical twin mirroring rates may be inflated or contingent upon phenotype. Instead, rates reported for this sample more closely align with the proposed etiology of this condition.

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IVF twins: buy one get one free?

Cited by 9 publications

References 40 publications

Promoting the use of elective single embryo transfer in clinical practice

Promoting the use of elective single embryo transfer in clinical practice

The ethics of fertility treatment for same-sex male couples: Considerations for a modern fertility clinic

Mirror, mirror? An evaluation of identical twin mirroring in tooth crown morphology

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