J0270202 Mitochondrial Dynamics in Endothelial Cells Dependent on Strain of Cyclic Stretch

Abstract

Cells are continuously exposed to the mechanical stimulus suGh as the cyclic stretch due to heart beats， The cells are aligned nearly perpendicular to the direction ofthe cyclic stretch． Recent reports ｛ ndicate that the pathological levels of cyclic stretch cause apoptosis ． The balance of the mitochondrial fUsion and fission influences the state of the ce1L