Jacob's Disease: A Case Report and Literature Review

Abstract

An 18-year old female patient presented for consultation at the Maxillofacial Surgery Department with a ten-year history of progressive restriction of mouth opening and mid facial asymmetry (Figure 1a and 1b).Clinical examination revealed marked restriction of mandibular movement with no pain, and maximum 20 mm interincisal mouth AbstractAlthough osteochondroma is the most common benign tumor of bone in the axial skeleton, it rarely involves the maxillofacial region. In the latter case, it mainly affects the mandible, particularly the condyle. Very occasionally, it may affect the coronoid process and lead to the formation of a pseudo joint with the zygoma, a condition termed Jacob's disease. This results in restricted mandibular movement and often causes midfacial asymmetry. We herein report the case of an 18 year-old female patient with a history of limited mouth opening for several years. Computed tomography and 3D reconstruction showed an exophytic tumor in the coronoid process, and a close relationship between the coronoid process and the malar and zygomatic arch. Total resection of the tumor and coronoid process was performed. Figure 2: a) Intra-oral osteotomy of the coronoid process. b) Surgical specimen. Coronoid process with the tumor. c) Maximum interincisal mouth opening 1 year post-surgery.

Osteocondroma de apófisis coronoides: enfermedad de Jacob

“…21 El abordaje intraoral (de nuestra preferencia) permite un acceso directo al proceso coronoideo eliminando el posible daño al nervio facial y cicatrices indeseables. [2][3][4]12,21 El pronóstico es excelente y las recidivas son raras.…”

“…1 Representa de 20 a 50% de todos los tumores óseos benignos y de 10 a 15% de los tumores óseos en total. 2 Rara vez ocurre en la región craneofacial (menos de 1%) siendo aún menos común en la apófisis coronoides. 3,4 La etiología del tumor no se ha comprendido del todo.…”