Jujube fruit: A potential nutritious fruit for the development of functional food products

Rashwan, Ahmed K.; Karim, Naymul; Shishir, Mohammad Rezaul Islam; Bao, Tao; Yang, Lu; Chen, Wei

doi:10.1016/j.jff.2020.104205

Cited by 150 publications

(113 citation statements)

References 75 publications

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“…Flavonoid is a kind of natural phenolic compound that have been shown to have a wide range of pharmacological effects, such as antiviral, anti-inflammatory and anti-obesity effects . [38][39][40] The total flavonoids content of the jujube fruit measured ranged from 7.07 mg/g DW of 'JS1H' to 41.18 mg/g DW of 'QXYZ,' which was higher than the content of flavonoids determined by Rashwan et al, [2] which was 0.7-1.8 g/100 g DW. The total polyphenol content in jujube fruit ranged from 8.45 mg GAE/g DW of 'JS4H' to 16.33 mg GAE/g DW of 'QXYZ,' which was similar than 8.76-21.61 mg GAE/ g determined by Ivanišová et al .…”

Section: Analysis Of Secondary Metabolites In Jujube Fruitmentioning

confidence: 54%

“…is a plant of the Rhamnaceae family, widely distributed in subtropical and tropical regions, especially in East Asia (China, Korea and India), the Middle East (Pakistan and Iran) and North African countries . [1][2][3] Jujube originated in China and has a history of planting for more than 4,000 years . [4] It is the world's largest red date producer and only red date exporter, accounting for more than 90% of the world's total red date output .…”

Section: Introductionmentioning

confidence: 99%

“…Other parts of jujube, such as seeds, fruits, leaves and flowers, are also used as medicinal preparations . [2,12,13] Among them, the edible part (pulp and peel) of jujube fruit is the focus of research, which contains most of the active active substances. Some studies have indicated that jujube contains a large number of active substances, such as polyphenol, flavonoid, triterpene, polysaccharide, ascorbic acid, cyclic adenosine monophosphate (cAMP) .…”

Section: Introductionmentioning

confidence: 99%

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Active components and antioxidant activity of thirty-seven varieties of Chinese jujube fruits (Ziziphus jujuba Mill.)

Zhang

Sun

Vidyarthi

et al. 2021

International Journal of Food Properties

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Jujube has received more and more attention due to their nutritional value and pharmacological effects. This study evaluated the quality of different varieties of jujube by comparing the main active components and antioxidant activities of thirty-seven varieties of jujube through titration, UV spectrophotometry and High performance liquid chromatography (HPLC). The results revealed that there were differences in active components and antioxidant capacity among jujube cultivars. Among the thirty-seven varieties of jujube, Qingxuyuanzao (QXYZ) had the highest contents of total phenols and flavonoids, which were 16.33 mg GAE/g DW and 41.18 mg RE/g DW, respectively, and had the highest free radical scavenging (DPPH: 29.79 mg Vc/g DW; ABTS: 50.90 mg Trolox/g DW) and reducing abilities (62.13 mg Trolox/g DW). Correlation analysis indicated that the content of total flavonoids, total phenols and phenolic acid ((+)catechin, caffeic acid, rutin) in jujube had high positive correlation with antioxidant capacity. According to principal component analysis (PCA), the comprehensive scores of different varieties of jujube were calculated. The top five jujube varieties with comprehensive scores are 'QXYZ,' Suyuanling (SYL), Xiangzao (XZ), Dunhuangdazao (DHDZ) and Meimizao (MMZ). In this paper, the main active components and antioxidant capacity of thirty-seven jujube varieties have been studied, which provides a theoretical basis for jujube breeding and the development of active nutrients for jujube.

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Section: Analysis Of Secondary Metabolites In Jujube Fruitmentioning

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Active components and antioxidant activity of thirty-seven varieties of Chinese jujube fruits (Ziziphus jujuba Mill.)

Zhang

Sun

Vidyarthi

et al. 2021

International Journal of Food Properties

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“…var. spinosa (Bunge) possess extensive sedative and hypnotic effects [ 18 ] and are therefore considered an important raw material in the food and pharmaceutical industries [ 19 ]. Recent investigations of Guo et al demonstrated that 100 g of Ziziphus jujuba var.…”

Section: Discussionmentioning

confidence: 99%

Flavonoid Glycosides from Ziziphus jujuba var. inermis (Bunge) Rehder Seeds Inhibit α-Melanocyte-Stimulating Hormone-Mediated Melanogenesis

Molagoda

Lee

Athapaththu

et al. 2021

IJMS

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Ziziphus jujuba extracts possess a broad spectrum of biological activities, such as antioxidant and anticancer activities in melanoma cancers. Nevertheless, the compounds contain high antioxidant capacities and anticancer activities in melanoma cells, shown to be effective in hyperpigmentation disorders, but whether flavonoid glycosides from Z. jujuba regulate anti-melanogenesis remains unclear. In this study, we evaluated the anti-melanogenic activity of five flavonoid glycosides from Z. jujuba var. inermis (Bunge) Rehder seeds, including jujuboside A (JUA), jujuboside B (JUB), epiceanothic acid (EPA), betulin (BTL), and 6’’’-feruloylspinosin (FRS), in B16F10 melanoma cells and zebrafish larvae. According to our results, JUB, EPA, and FRS potently inhibited α-melanocyte-stimulating hormone (α-MSH)-induced melanogenesis and prevented hyperpigmentation in zebrafish larvae. In particular, under α-MSH-stimulated conditions, FRS most significantly inhibited α-MSH-induced intracellular and extracellular melanin content in B16F10 melanoma cells. Additionally, JUB, EPS, and FRS remarkably downregulated melanogenesis in α-MSH-treated zebrafish larvae, with no significant change in heart rate. Neither JUA nor BTA were effective in downregulating melanogenesis in B16F10 melanoma cells and zebrafish larvae. Furthermore, JUB, EPA, and FRS directly inhibited in vitro mushroom tyrosinase enzyme activity. JUB, EPA, and FRS also downregulated cyclic adenosine monophosphate (cAMP) levels and the phosphorylation of cAMP-response element-binding protein (CREB), and subsequent microphthalmia transcription factor (MITF) and tyrosinase expression. In conclusion, this study demonstrated that JUB, EPA, and FRS isolated from Z. jujuba var. inermis (Bunge) Rehder seeds exhibit potent anti-melanogenic properties by inhibition of the cAMP-CERB-MITF axis and consequent tyrosinase activity.

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“…Nowadays, with the evolution of scientific and technological methods, the nutritional Review https://doi.org/10.1631/jzus. B2000594 et al, 2015;Hernández et al, 2016;Rashwan et al, 2020). Based on the literature, bioactive compounds extracted from jujube have various bioactivity, including antioxidant (Zhang et al, 2010;Zhao HX et al, 2014), anti-inflammatory (Yu et al, 2012), anticancer (Choi et al, 2012;Plastina et al, 2012), anti-hyperglycemic (Kawabata et al, 2017), anti-hyperlipidemic (Jeong and Kim, 2019), immunomodulatory (Dash et al, 2015), and other activity.…”

Section: Introductionmentioning

confidence: 99%

Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit

Yang

Bao

et al. 2021

J. Zhejiang Univ. Sci. B

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Jujube (Ziziphus jujuba Mill.), a highly nutritious and functional fruit, is reported to have various health benefits and has been extensively planted worldwide, especially in China. Many studies have shown that bioactive components derived from jujube fruit have significant nutritional and potential biological effects. In this paper, the latest progress in research on major bioactive compounds obtained from jujube is reviewed, and the potential biological functions of jujube fruit resources are discussed. As a dietary supplement, jujube fruit is well recognized as a healthy food which contains a variety of bioactive substances, such as polysaccharides, polyphenols, amino acids, nucleotides, fatty acids, dietary fiber, alkaloids, and other nutrients. These nutrients and non-nutritive phytochemicals obtained from jujube fruit have physiological functions including anticancer, antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-hyperglycemic, immunoregulatory, neuroprotective, sedative, and antiviral functions. Of note is that new constituents, including alkaloids, dietary fiber, and other bioactive substances, as well as the antiviral, hypoglycemic, lipid-lowering, and neuroprotective effects of jujube fruit, are systematically reviewed here for the first time. Meanwhile, problems affecting the exploitation of jujube fruit resources are discussed and further research directions proposed. Therefore, this review provides a useful bibliography for the future development of jujube-based products and the utilization of jujube nutritional components in functional foods.

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Jujube fruit: A potential nutritious fruit for the development of functional food products

Cited by 150 publications

References 75 publications

Active components and antioxidant activity of thirty-seven varieties of Chinese jujube fruits (Ziziphus jujuba Mill.)

Active components and antioxidant activity of thirty-seven varieties of Chinese jujube fruits (Ziziphus jujuba Mill.)

Flavonoid Glycosides from Ziziphus jujuba var. inermis (Bunge) Rehder Seeds Inhibit α-Melanocyte-Stimulating Hormone-Mediated Melanogenesis

Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit

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