Just Beneath the Surface

Marshall, Catherine Handy; Nahas-Vigon, Jordan H.; Manesh, Reza; Gelber, Allan C.

doi:10.1056/nejmcps1802664

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…Risk groups include exposed professionals, and pregnant women, immunocompromised patients, and patients with valvular disease at risk for chronic Q fever after acute infection (Million et al, 2013). Currently, the greatest risk factor is living in or traveling to an endemic area (Hartzell et al, 2008;Hackert et al, 2012;Stern et al, 2018;Handy Marshall et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new

Rodríguez‐Alonso

Almeida²,

Alonso‐Sardón

et al. 2020

International Journal of Infectious Diseases

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A B S T R A C TObjectives: The objective of this study was to assess the epidemiology and burden of Q fever (QF) in Spain. Methods: We designed a retrospective descriptive study using the minimum basic data set in patients admitted to hospitals of the National Health System between 1998 and 2015 with a diagnosis of Q fever (ICD-9: 083.0.). Results: We found 4214 hospitalized patients with a mean age (AESD) of 50.9 AE 19.3 years. The male/ female ratio was 3:1. The incidence rate was between 0.41 and 0.65 cases per 100,000 person-years over the 18-year period. The highest incidence of cases was from March to August (p = 0.024). 21.1% patients had pneumonia, 17.5% had liver disease, and only 3.2% had endocarditis. The average hospital stay was 13.8 days (AE12.8). A total of 117 (2.8%) patients died. The total mean cost of QF is approximately s154,232,779 (s36,600 AE 139,422 per patient). Conclusions: QF is an important zoonosis in Spain with a stable incidence rate and high cost for hospitalization. Older patients have a more severe clinical picture and higher mortality, which can be decreased with early clinical suspicion.

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