Juxtacortical Mandibular Chondrosarcoma during pregnancy: A case report

Abstract

Chondrosarcoma is one of the most common malignant bone tumors in adults. It use to affect upper arm, pelvis and thigh bone. A wide surgical extirpation represent the gold standard to treat this disorder. In fact, radiotherapy and chemotherapy are no useful. Interestingly, chondrosarcoma is rare in head and neck (HNCS) and extremely uncommon during pregnancy. Thus, there is a lack of evidence about the proper treatment in these cases. A wide surgical extirpation is also considered the most effective procedure in HNCS. There are no consistent evidences about the he role of radiation and chemotherapy. In view of that, the present study describes a case of juxtacortical mandibular chondrosarcoma affecting a 28-year-old pregnant woman. After a multidisciplinary analysis of the case, we decided to treat the patient with a wide surgical resection and and immediately reconstruction. Key words:Mandibular chondrosarcoma, pregnancy, surgical extirpation, radiotherapy, chemoteraphy.

A rare case of primary ovarian mesenchymal chondrosarcoma in pregnancy

“…It has also been suggested that primary pure heterologous sarcomas may arise from primitive embryonal cell remnants or from a complete stromal overgrowth of a Mullerian mixed tumor. Another etiology appears to be related to the uncontrolled proliferation of Merkel cells (embryonic remains) [1,2]. Chondrosarcoma is also uncommon during pregnancy, and to the best of our knowledge no cases of proven primary ovarian chondrosarcoma in pregnancy have been reported in the literature; with regard to chondrosarcoma arising primarily in the ovary, only two cases have been reported in the English-language literature [6].…”

“…The effect of pregnancy on the growth features of chondrosarcomas remains unclear. Some experts have suggested a growth-enhancing effect of altered hormone levels on various bone tumors during pregnancy [2]. In addition, it still remains unclear whether chondrosarcoma during pregnancy may show progression or dedifferentiation according to the changes in hormonal status [1].…”

“…The purpose of this report is to describe the clinical and pathologic features of primary mesenchymal chondrosarcoma of the ovary as an exceedingly rare entity, specifically during pregnancy [1]. Chondrosarcoma is a malignant cartilaginous tumor characterized by the formation of cartilage, but not of bone, by tumor cells and it is the third most common primary malignant bone tumor in adults [2,3].…”

Head and Neck Juxtacortical Chondrosarcoma: A Systematic Review

“…The remaining 169 articles were subjected to full-text evaluation. After comprehensive review, 161 articles were excluded, leaving 8 articles as eligible for final inclusion in this systematic review[12][13][14][15][16][17][18][19].…”