Kaempferol alleviates bisphenol A reproductive toxicity in rats in a dose-dependent manner

Molayousefian, Inas; Karim, Bardia; Hosseini, Seyed Mohammad; Moghadamnia, Ali Akbar; Kazemi, Sohrab

doi:10.1016/j.bbrc.2024.149674

Biochemical and Biophysical Research Communications

2024

DOI: 10.1016/j.bbrc.2024.149674

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Kaempferol alleviates bisphenol A reproductive toxicity in rats in a dose-dependent manner

Inas Molayousefian,

Bardia Karim,

Seyed Mohammad Hosseini

et al.

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Environmental toxins and reproductive health: unraveling the effects on Sertoli cells and the blood–testis barrier in animals

Jiang,

Yang,

Peng

2024

Biology of Reproduction

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Environmental pollution is an inevitable ecological issue accompanying the process of socialization, with increasing attention to its impacts on individual organisms and ecological chains. The reproductive system, responsible for transmitting genetic material in animals, is one of the most sensitive systems to environmental toxins. Research reveals that Sertoli cells are the primary target cells for the action of environmental toxins. Different environmental toxins mostly affect the blood-testis barrier and lead to male reproductive disorders by disrupting Sertoli cells. Therefore, this article provides an in-depth exploration of the toxic mechanisms of various types of environmental toxins on the male testes. It reveals the dynamic processes of tight junctions in the blood-testis barrier affected by environmental toxins and their specific roles in the reconstruction process.

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Environmental toxins and reproductive health: unraveling the effects on Sertoli cells and the blood–testis barrier in animals

Jiang,

Yang,

Peng

2024

Biology of Reproduction

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show abstract

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Kaempferol alleviates bisphenol A reproductive toxicity in rats in a dose-dependent manner

Cited by 1 publication

References 64 publications

Environmental toxins and reproductive health: unraveling the effects on Sertoli cells and the blood–testis barrier in animals

Environmental toxins and reproductive health: unraveling the effects on Sertoli cells and the blood–testis barrier in animals

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