Karo’s Local Wisdom: The Use of Woody Plants for Traditional Diabetic Medicines

Anti-cholesterol triterpenoid acids from Saurauia vulcani Korth. (Actinidiaceae)

“…A comparison of the NMR data of 2 with 3,19-Dihydroxy-12-ursen-28-oic acid revealed that the structures of two compounds are very similar. [11] Therefore, compound 2 was identified as a 3,19-Dihydroxyurs-12-en-28oic acid (2). The isolated compounds 1-2 were first reported from this plant.…”

“…Two triterpenoids, 3β-hydroxy-Olean-12-en-28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia Vulcani. Korth (Actinidiaceae).…”

“…(Actinidiaceae) is known as pirdot plant and mainly distributed in a tropical climate. [1] This plant has not been researched well and less information about its phytochemical studies; however, its biological screening exhibited interesting pharmacological properties, including antihyperglycemic, antihyperlipidemic, [1] anti-diabetes, [2,3] anti-cancer, [4] antihypoglycemic, [5] and antioxidant. [6] Recently, our group screened the presence of triterpenoid compound from the leaves of Saurauia vulcani Korth.…”

“…[6] Recently, our group screened the presence of triterpenoid compound from the leaves of Saurauia vulcani Korth. [7] As a part of our continuing search for active compounds from this plant, we isolated and described the triterpenoid compounds, 3β-hydroxy-Olean-12-en-28-oic acid (1) and 3,19-Dihydroxyurs -12-en-28-oic acid (2). These compounds were first reported from this plant.…”