Ketofol as induction agent in diabetic patients.

Abstract

Objective: To evaluate the role of ketofol as induction agent in diabetic patients. Study Design: Randomized Control Trial. Setting: Department of Anesthesia, Abwa Medical College, Faisalabad. Period: 01-12-21 to 01-05-22. Material & Methods: Patients after informed consent divided randomly into two groups 25 in each. Group A receiving propofol 1.5 mg/kg and Group B receiving ketofol 1:2 as induction agent. The dose given was 1ml for every 5Kg. Standard 5 parameter monitoring with pulse oximetry, ECG, non invasive BP done starting from preoperative to 2 minutes, 5 minutes and 10 minutes after induction agent given. MAP and HR were monitored. Hemodynamic instability was defined as I) Heart rate >160/min or <50/min. II) MAP>120mmHg or <60 mm Hg. Results: Total 50 patients included in this study. 25 in each group. The results show significant stability in hemodynamics in group B. Conclusion: Ketofol has better hemodynamic stability as induction agent in diabetic patients when used in a 2:1 ratio. This makes it a good choice for this specific patient population.